A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Using a Low-Frequency Magnetic Field in the Treatment of Musculoskeletal Chronic Pain
Exposure to a specific pulsed electromagnetic field (PEMF) has been shown to produce analgesic (antinociceptive) effects in many organisms. In a randomized, double-blind, sham-controlled clinical trial, patients with either chronic generalized pain from fibromyalgia (FM) or chronic localized musculo...
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2007/626072 |
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| _version_ | 1850168067038904320 |
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| author | Alex W Thomas Karissa Graham Frank S Prato Julia McKay Patricia Morley Forster Dwight E Moulin Sesh Chari |
| author_facet | Alex W Thomas Karissa Graham Frank S Prato Julia McKay Patricia Morley Forster Dwight E Moulin Sesh Chari |
| author_sort | Alex W Thomas |
| collection | DOAJ |
| description | Exposure to a specific pulsed electromagnetic field (PEMF) has been shown to produce analgesic (antinociceptive) effects in many organisms. In a randomized, double-blind, sham-controlled clinical trial, patients with either chronic generalized pain from fibromyalgia (FM) or chronic localized musculoskeletal or inflammatory pain were exposed to a PEMF (400 μT) through a portable device fitted to their head during twice-daily 40 min treatments over seven days. The effect of this PEMF on pain reduction was recorded using a visual analogue scale. A differential effect of PEMF over sham treatment was noticed in patients with FM, which approached statistical significance (P=0.06) despite low numbers (n=17); this effect was not evident in those without FM (P=0.93; n=15). PEMF may be a novel, safe and effective therapeutic tool for use in at least certain subsets of patients with chronic, nonmalignant pain. Clearly, however, a larger randomized, double-blind clinical trial with just FM patients is warranted. |
| format | Article |
| id | doaj-art-e64bdd2e421b4cedaf200e69a28c6132 |
| institution | OA Journals |
| issn | 1203-6765 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-e64bdd2e421b4cedaf200e69a28c61322025-08-20T02:21:03ZengWileyPain Research and Management1203-67652007-01-0112424925810.1155/2007/626072A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Using a Low-Frequency Magnetic Field in the Treatment of Musculoskeletal Chronic PainAlex W Thomas0Karissa Graham1Frank S Prato2Julia McKay3Patricia Morley Forster4Dwight E Moulin5Sesh Chari6Bioelectromagnetics, Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, Department of Nuclear Medicine, CanadaBioelectromagnetics, Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, Department of Nuclear Medicine, CanadaBioelectromagnetics, Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, Department of Nuclear Medicine, CanadaBioelectromagnetics, Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, Department of Nuclear Medicine, CanadaDepartment of Anesthesiology, St Joseph’s Hospital, CanadaInterdisciplinary Pain Program, University of Western Ontario, London, CanadaFralex Therapeutics Inc, Toronto, Ontario, CanadaExposure to a specific pulsed electromagnetic field (PEMF) has been shown to produce analgesic (antinociceptive) effects in many organisms. In a randomized, double-blind, sham-controlled clinical trial, patients with either chronic generalized pain from fibromyalgia (FM) or chronic localized musculoskeletal or inflammatory pain were exposed to a PEMF (400 μT) through a portable device fitted to their head during twice-daily 40 min treatments over seven days. The effect of this PEMF on pain reduction was recorded using a visual analogue scale. A differential effect of PEMF over sham treatment was noticed in patients with FM, which approached statistical significance (P=0.06) despite low numbers (n=17); this effect was not evident in those without FM (P=0.93; n=15). PEMF may be a novel, safe and effective therapeutic tool for use in at least certain subsets of patients with chronic, nonmalignant pain. Clearly, however, a larger randomized, double-blind clinical trial with just FM patients is warranted.http://dx.doi.org/10.1155/2007/626072 |
| spellingShingle | Alex W Thomas Karissa Graham Frank S Prato Julia McKay Patricia Morley Forster Dwight E Moulin Sesh Chari A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Using a Low-Frequency Magnetic Field in the Treatment of Musculoskeletal Chronic Pain Pain Research and Management |
| title | A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Using a Low-Frequency Magnetic Field in the Treatment of Musculoskeletal Chronic Pain |
| title_full | A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Using a Low-Frequency Magnetic Field in the Treatment of Musculoskeletal Chronic Pain |
| title_fullStr | A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Using a Low-Frequency Magnetic Field in the Treatment of Musculoskeletal Chronic Pain |
| title_full_unstemmed | A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Using a Low-Frequency Magnetic Field in the Treatment of Musculoskeletal Chronic Pain |
| title_short | A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Using a Low-Frequency Magnetic Field in the Treatment of Musculoskeletal Chronic Pain |
| title_sort | randomized double blind placebo controlled clinical trial using a low frequency magnetic field in the treatment of musculoskeletal chronic pain |
| url | http://dx.doi.org/10.1155/2007/626072 |
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