Malignant pleural mesothelioma with rarely seen metastases

Malignant mesothelioma, primarily located in the pleura, is a locally aggressive tumor. Distant metastases are rarely seen and mostly diagnosed postmortem. We present the third malignant pleural mesothelioma (MPM) case in the literature with bone marrow metastasis. A 36-year-old male patient present...

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Main Authors: Elif Şenocak Taşçı, Gül Akın, Birgül Öneç, Onur Eşbah
Format: Article
Language:English
Published: Galenos Publishing House 2017-12-01
Series:Journal of Oncological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452336417300560
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author Elif Şenocak Taşçı
Gül Akın
Birgül Öneç
Onur Eşbah
author_facet Elif Şenocak Taşçı
Gül Akın
Birgül Öneç
Onur Eşbah
author_sort Elif Şenocak Taşçı
collection DOAJ
description Malignant mesothelioma, primarily located in the pleura, is a locally aggressive tumor. Distant metastases are rarely seen and mostly diagnosed postmortem. We present the third malignant pleural mesothelioma (MPM) case in the literature with bone marrow metastasis. A 36-year-old male patient presented with pain at the right mediastinal area and 5 × 6cm mass on the right side of his chest. 18-FDG positron emission tomography (PET) scan showed local uptake at the pleura, regional lymph nodes and 5th rib. The tru-cut biopsy reported as sarcomatoid type MPM. Cisplatin-pemetrexed therapy was planned. His medical condition deteriorated after 2 months and multiple metastases to brain, liver, adrenal glands and bone marrow were detected. The patient was lost 4 months after he was diagnosed. Brain and bone marrow metastasis of MPM are rarely seen. Physicians should be careful about the rapid progression and unexpected metastases of MPM.
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spelling doaj-art-e648ac4a73f2471bac81ccac62cf8fe22025-08-20T03:57:59ZengGalenos Publishing HouseJournal of Oncological Sciences2452-33642017-12-013313313410.1016/j.jons.2017.11.003Malignant pleural mesothelioma with rarely seen metastasesElif Şenocak Taşçı0Gül Akın1Birgül Öneç2Onur Eşbah3Düzce University Faculty of Medicine, Department of Internal Medicine, Düzce, TurkeyDüzce University Faculty of Medicine, Department of Internal Medicine, Düzce, TurkeyDüzce University Faculty of Medicine, Department of Internal Medicine, Division of Haematology, Düzce, TurkeyDüzce University Faculty of Medicine, Department of Internal Medicine, Division of Oncology, Düzce, TurkeyMalignant mesothelioma, primarily located in the pleura, is a locally aggressive tumor. Distant metastases are rarely seen and mostly diagnosed postmortem. We present the third malignant pleural mesothelioma (MPM) case in the literature with bone marrow metastasis. A 36-year-old male patient presented with pain at the right mediastinal area and 5 × 6cm mass on the right side of his chest. 18-FDG positron emission tomography (PET) scan showed local uptake at the pleura, regional lymph nodes and 5th rib. The tru-cut biopsy reported as sarcomatoid type MPM. Cisplatin-pemetrexed therapy was planned. His medical condition deteriorated after 2 months and multiple metastases to brain, liver, adrenal glands and bone marrow were detected. The patient was lost 4 months after he was diagnosed. Brain and bone marrow metastasis of MPM are rarely seen. Physicians should be careful about the rapid progression and unexpected metastases of MPM.http://www.sciencedirect.com/science/article/pii/S2452336417300560Bone marrowLiverBrainMetastasis
spellingShingle Elif Şenocak Taşçı
Gül Akın
Birgül Öneç
Onur Eşbah
Malignant pleural mesothelioma with rarely seen metastases
Journal of Oncological Sciences
Bone marrow
Liver
Brain
Metastasis
title Malignant pleural mesothelioma with rarely seen metastases
title_full Malignant pleural mesothelioma with rarely seen metastases
title_fullStr Malignant pleural mesothelioma with rarely seen metastases
title_full_unstemmed Malignant pleural mesothelioma with rarely seen metastases
title_short Malignant pleural mesothelioma with rarely seen metastases
title_sort malignant pleural mesothelioma with rarely seen metastases
topic Bone marrow
Liver
Brain
Metastasis
url http://www.sciencedirect.com/science/article/pii/S2452336417300560
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