Potential pathogenic and protective genotypes and phenotypes of vitamin D binding protein in multiple sclerosis
BackgroundThe main carrier protein of vitamin D and its metabolites in plasma is vitamin D binding protein (VDBP) or group-specific component (Gc). Two single nucleotide polymorphisms, rs7041, and rs4588 in the GC gene result in three major VDBP/Gc genotypes, GC1F (c.1296T, c.1307C), GC1S (c.1296G,...
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Main Authors: | Suhail Al-Shammri, Arpita Chattopadhyay, Abu Salim Mustafa |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-02-01
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Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1455779/full |
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