Anaplastic sarcoma of the kidney: Case report and literature review
We present a case of a 22-year-old female with gross hematuria for 1 month. A 9.5-cm tumor was found at her left kidney. On suspicion of a renal cancer, she received left nephrectomy. Histologically, it was a hypercellular tumor with undifferentiated anaplastic neoplastic cells in fascicular sheets...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Tzu Chi Medical Journal |
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| Online Access: | http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2019;volume=31;issue=2;spage=129;epage=132;aulast=Chen |
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| _version_ | 1850194308786814976 |
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| author | Chien-Chin Chen Kai-Sheng Liao |
| author_facet | Chien-Chin Chen Kai-Sheng Liao |
| author_sort | Chien-Chin Chen |
| collection | DOAJ |
| description | We present a case of a 22-year-old female with gross hematuria for 1 month. A 9.5-cm tumor was found at her left kidney. On suspicion of a renal cancer, she received left nephrectomy. Histologically, it was a hypercellular tumor with undifferentiated anaplastic neoplastic cells in fascicular sheets intermixed with chondroid nodules. The differential diagnoses included anaplastic sarcoma of the kidney (ASK), anaplastic Wilms tumor, mesenchymal chondrosarcoma, sarcomatoid renal cell carcinoma, clear cell sarcoma of the kidney, rhabdoid tumor of the kidney, congenital mesoblastic nephroma, and synovial sarcoma. Based on the results of the work-up and literature review, ASK was diagnosed. The postoperative recovery was uneventful, and the patient began adjuvant chemotherapy (Ifosfamide [1800 mg/m2] and Epirubicin [60 mg/m2]) 5 weeks after the operation. Herein, we present this case to share the experience on an extremely rare entity. |
| format | Article |
| id | doaj-art-e6400ae6ea7e407492f70a33879a762f |
| institution | OA Journals |
| issn | 1016-3190 2223-8956 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Tzu Chi Medical Journal |
| spelling | doaj-art-e6400ae6ea7e407492f70a33879a762f2025-08-20T02:14:01ZengWolters Kluwer Medknow PublicationsTzu Chi Medical Journal1016-31902223-89562019-01-0131212913210.4103/tcmj.tcmj_194_18Anaplastic sarcoma of the kidney: Case report and literature reviewChien-Chin ChenKai-Sheng LiaoWe present a case of a 22-year-old female with gross hematuria for 1 month. A 9.5-cm tumor was found at her left kidney. On suspicion of a renal cancer, she received left nephrectomy. Histologically, it was a hypercellular tumor with undifferentiated anaplastic neoplastic cells in fascicular sheets intermixed with chondroid nodules. The differential diagnoses included anaplastic sarcoma of the kidney (ASK), anaplastic Wilms tumor, mesenchymal chondrosarcoma, sarcomatoid renal cell carcinoma, clear cell sarcoma of the kidney, rhabdoid tumor of the kidney, congenital mesoblastic nephroma, and synovial sarcoma. Based on the results of the work-up and literature review, ASK was diagnosed. The postoperative recovery was uneventful, and the patient began adjuvant chemotherapy (Ifosfamide [1800 mg/m2] and Epirubicin [60 mg/m2]) 5 weeks after the operation. Herein, we present this case to share the experience on an extremely rare entity.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2019;volume=31;issue=2;spage=129;epage=132;aulast=ChenAnaplastic sarcomaMesenchymal chondrosarcomaRenal tumorSarcomatoid carcinomaWilms tumor |
| spellingShingle | Chien-Chin Chen Kai-Sheng Liao Anaplastic sarcoma of the kidney: Case report and literature review Tzu Chi Medical Journal Anaplastic sarcoma Mesenchymal chondrosarcoma Renal tumor Sarcomatoid carcinoma Wilms tumor |
| title | Anaplastic sarcoma of the kidney: Case report and literature review |
| title_full | Anaplastic sarcoma of the kidney: Case report and literature review |
| title_fullStr | Anaplastic sarcoma of the kidney: Case report and literature review |
| title_full_unstemmed | Anaplastic sarcoma of the kidney: Case report and literature review |
| title_short | Anaplastic sarcoma of the kidney: Case report and literature review |
| title_sort | anaplastic sarcoma of the kidney case report and literature review |
| topic | Anaplastic sarcoma Mesenchymal chondrosarcoma Renal tumor Sarcomatoid carcinoma Wilms tumor |
| url | http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2019;volume=31;issue=2;spage=129;epage=132;aulast=Chen |
| work_keys_str_mv | AT chienchinchen anaplasticsarcomaofthekidneycasereportandliteraturereview AT kaishengliao anaplasticsarcomaofthekidneycasereportandliteraturereview |