Diagnosis and Management Challenges of Spontaneous Quadruplet Pregnancy in a Resource-Limited Setting: A Case Report

Kevin Dominique Tjandraprawira,1 Dhanny Primantara Johari Santoso,2 Hartanto Bayuaji,1 Annisa Dewi Nugrahani,2 Dadan Susandi2 1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Bandung, Indonesia; 2Department of Obstetrics and...

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Main Authors: Tjandraprawira KD, Santoso DPJ, Bayuaji H, Nugrahani AD, Susandi D
Format: Article
Language:English
Published: Dove Medical Press 2025-03-01
Series:International Medical Case Reports Journal
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Online Access:https://www.dovepress.com/diagnosis-and-management-challenges-of-spontaneous-quadruplet-pregnanc-peer-reviewed-fulltext-article-IMCRJ
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author Tjandraprawira KD
Santoso DPJ
Bayuaji H
Nugrahani AD
Susandi D
author_facet Tjandraprawira KD
Santoso DPJ
Bayuaji H
Nugrahani AD
Susandi D
author_sort Tjandraprawira KD
collection DOAJ
description Kevin Dominique Tjandraprawira,1 Dhanny Primantara Johari Santoso,2 Hartanto Bayuaji,1 Annisa Dewi Nugrahani,2 Dadan Susandi2 1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Bandung, Indonesia; 2Department of Obstetrics and Gynecology, Dr. Slamet General Hospital, Garut, IndonesiaCorrespondence: Kevin Dominique Tjandraprawira, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, Email kevin14007@mail.unpad.ac.idIntroduction: Higher-order pregnancy is considered as a high-risk pregnancy, followed by various maternal and foetal complications. The diagnosis and management of higher order pregnancy have abundant and complex challenges, especially in rural areas where antenatal care (ANC) is often inadequate. Late booking and low awareness of complications necessitates priority management and referral to a tertiary center for fetal medicine expertise. This is our experience managing a spontaneously conceived quadruplet pregnancy delivered prematurely in a low-resource setting.Case Presentations: A 27-years-old primigravida of 7.5 months of gestation presented with preterm labor. Her membrane was intact, and she noted active fetal movements. Her history was notable due to her pregnancy being spontaneously conceived and that her antenatal consultations had mistakenly identified her pregnancy as a triplet pregnancy. At presentation, her fundal height was 49 cm, and her cervix was 5– 6 cm dilated. As she was in active labor, she underwent an emergency caesarean section. Four neonates were delivered but only two were transferred to the neonatal intensive care unit due to infrastructure limitations. She made an uneventful recovery and was discharged 2 days later. However, only two of four neonates eventually survived. This quadruplet pregnancy signified the pertinent complications of multifetal pregnancy: misidentification of chorionicity; preterm delivery; and early neonatal deaths due to prematurity.Conclusion: Higher order pregnancies present their own challenges for diagnosis and treatment. Preterm delivery and its associated neonatal complications are well-known complications, and a multidisciplinary management is crucial.Keywords: case report, multiple pregnancy, pregnancy, quadruplet
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spelling doaj-art-e63fa164c41f43708b56da0ef549e4402025-08-20T01:57:20ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2025-03-01Volume 18325332100974Diagnosis and Management Challenges of Spontaneous Quadruplet Pregnancy in a Resource-Limited Setting: A Case ReportTjandraprawira KDSantoso DPJBayuaji HNugrahani ADSusandi DKevin Dominique Tjandraprawira,1 Dhanny Primantara Johari Santoso,2 Hartanto Bayuaji,1 Annisa Dewi Nugrahani,2 Dadan Susandi2 1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Bandung, Indonesia; 2Department of Obstetrics and Gynecology, Dr. Slamet General Hospital, Garut, IndonesiaCorrespondence: Kevin Dominique Tjandraprawira, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, Email kevin14007@mail.unpad.ac.idIntroduction: Higher-order pregnancy is considered as a high-risk pregnancy, followed by various maternal and foetal complications. The diagnosis and management of higher order pregnancy have abundant and complex challenges, especially in rural areas where antenatal care (ANC) is often inadequate. Late booking and low awareness of complications necessitates priority management and referral to a tertiary center for fetal medicine expertise. This is our experience managing a spontaneously conceived quadruplet pregnancy delivered prematurely in a low-resource setting.Case Presentations: A 27-years-old primigravida of 7.5 months of gestation presented with preterm labor. Her membrane was intact, and she noted active fetal movements. Her history was notable due to her pregnancy being spontaneously conceived and that her antenatal consultations had mistakenly identified her pregnancy as a triplet pregnancy. At presentation, her fundal height was 49 cm, and her cervix was 5– 6 cm dilated. As she was in active labor, she underwent an emergency caesarean section. Four neonates were delivered but only two were transferred to the neonatal intensive care unit due to infrastructure limitations. She made an uneventful recovery and was discharged 2 days later. However, only two of four neonates eventually survived. This quadruplet pregnancy signified the pertinent complications of multifetal pregnancy: misidentification of chorionicity; preterm delivery; and early neonatal deaths due to prematurity.Conclusion: Higher order pregnancies present their own challenges for diagnosis and treatment. Preterm delivery and its associated neonatal complications are well-known complications, and a multidisciplinary management is crucial.Keywords: case report, multiple pregnancy, pregnancy, quadruplethttps://www.dovepress.com/diagnosis-and-management-challenges-of-spontaneous-quadruplet-pregnanc-peer-reviewed-fulltext-article-IMCRJcase reportmultiple pregnancypregnancyquadruplet
spellingShingle Tjandraprawira KD
Santoso DPJ
Bayuaji H
Nugrahani AD
Susandi D
Diagnosis and Management Challenges of Spontaneous Quadruplet Pregnancy in a Resource-Limited Setting: A Case Report
International Medical Case Reports Journal
case report
multiple pregnancy
pregnancy
quadruplet
title Diagnosis and Management Challenges of Spontaneous Quadruplet Pregnancy in a Resource-Limited Setting: A Case Report
title_full Diagnosis and Management Challenges of Spontaneous Quadruplet Pregnancy in a Resource-Limited Setting: A Case Report
title_fullStr Diagnosis and Management Challenges of Spontaneous Quadruplet Pregnancy in a Resource-Limited Setting: A Case Report
title_full_unstemmed Diagnosis and Management Challenges of Spontaneous Quadruplet Pregnancy in a Resource-Limited Setting: A Case Report
title_short Diagnosis and Management Challenges of Spontaneous Quadruplet Pregnancy in a Resource-Limited Setting: A Case Report
title_sort diagnosis and management challenges of spontaneous quadruplet pregnancy in a resource limited setting a case report
topic case report
multiple pregnancy
pregnancy
quadruplet
url https://www.dovepress.com/diagnosis-and-management-challenges-of-spontaneous-quadruplet-pregnanc-peer-reviewed-fulltext-article-IMCRJ
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