Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute Stroke
Loss of motor coordination is one of the main problems for patients after stroke. Muscle synergy is widely accepted as an indicator of motor coordination. Recently, the characteristics of muscle synergy were quantitatively evaluated using nonnegative matrix factorization (NNMF) with surface electrom...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2016/5282957 |
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| author | Yu Hashiguchi Koji Ohata Ryosuke Kitatani Natsuki Yamakami Kaoru Sakuma Sayuri Osako Yumi Aga Aki Watanabe Shigehito Yamada |
| author_facet | Yu Hashiguchi Koji Ohata Ryosuke Kitatani Natsuki Yamakami Kaoru Sakuma Sayuri Osako Yumi Aga Aki Watanabe Shigehito Yamada |
| author_sort | Yu Hashiguchi |
| collection | DOAJ |
| description | Loss of motor coordination is one of the main problems for patients after stroke. Muscle synergy is widely accepted as an indicator of motor coordination. Recently, the characteristics of muscle synergy were quantitatively evaluated using nonnegative matrix factorization (NNMF) with surface electromyography. Previous studies have identified that the number and structure of synergies were associated with motor function in patients after stroke. However, most of these studies had a cross-sectional design, and the changes in muscle synergy during recovery process are not clear. In present study, two consecutive measurements were conducted for subacute patients after stroke and the change of number and structure of muscle synergies during gait were determined using NNMF. Results showed that functional change did not rely on number of synergies in patients after subacute stroke. However, the extent of merging of the synergies was negatively associated with an increase in muscle strength and the range of angle at ankle joint. Our results suggest that the neural changes represented by NNMF were related to the longitudinal change of function and gait pattern and that the merging of synergy is an important marker in patients after subacute stroke. |
| format | Article |
| id | doaj-art-e63819100ef84ca6914b99b3c5ebe32c |
| institution | OA Journals |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-e63819100ef84ca6914b99b3c5ebe32c2025-08-20T02:21:02ZengWileyNeural Plasticity2090-59041687-54432016-01-01201610.1155/2016/52829575282957Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute StrokeYu Hashiguchi0Koji Ohata1Ryosuke Kitatani2Natsuki Yamakami3Kaoru Sakuma4Sayuri Osako5Yumi Aga6Aki Watanabe7Shigehito Yamada8Department of Physical Therapy, Faculty of Health Science, Gumma Paz College, Gunma, JapanDepartment of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, JapanKansai Rehabilitation Hospital, Osaka, JapanFujita Health University Hospital, Aichi, JapanDepartment of Rehabilitation Sciences, Kansai University of Welfare Science, Osaka, JapanKuretake Special Support School, Kyoto, JapanAijinkai Rehabilitation Hospital, Osaka, JapanOita Tobu Hospital, Oita, JapanDepartment of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, JapanLoss of motor coordination is one of the main problems for patients after stroke. Muscle synergy is widely accepted as an indicator of motor coordination. Recently, the characteristics of muscle synergy were quantitatively evaluated using nonnegative matrix factorization (NNMF) with surface electromyography. Previous studies have identified that the number and structure of synergies were associated with motor function in patients after stroke. However, most of these studies had a cross-sectional design, and the changes in muscle synergy during recovery process are not clear. In present study, two consecutive measurements were conducted for subacute patients after stroke and the change of number and structure of muscle synergies during gait were determined using NNMF. Results showed that functional change did not rely on number of synergies in patients after subacute stroke. However, the extent of merging of the synergies was negatively associated with an increase in muscle strength and the range of angle at ankle joint. Our results suggest that the neural changes represented by NNMF were related to the longitudinal change of function and gait pattern and that the merging of synergy is an important marker in patients after subacute stroke.http://dx.doi.org/10.1155/2016/5282957 |
| spellingShingle | Yu Hashiguchi Koji Ohata Ryosuke Kitatani Natsuki Yamakami Kaoru Sakuma Sayuri Osako Yumi Aga Aki Watanabe Shigehito Yamada Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute Stroke Neural Plasticity |
| title | Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute Stroke |
| title_full | Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute Stroke |
| title_fullStr | Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute Stroke |
| title_full_unstemmed | Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute Stroke |
| title_short | Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute Stroke |
| title_sort | merging and fractionation of muscle synergy indicate the recovery process in patients with hemiplegia the first study of patients after subacute stroke |
| url | http://dx.doi.org/10.1155/2016/5282957 |
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