High-risk human papillomavirus testing in first-void urine as a novel and non-invasive cervical cancer screening modality—a Danish diagnostic test accuracy study

High-risk human papillomavirus testing in first-void urine as a novel and non-invasive cervical cancer screening modality—a Danish diagnostic test accuracy study

Abstract Background First-void urine (FVU) collection for high-risk human papillomavirus (hrHPV) testing has game-changing potential to improve cervical cancer prevention among under-screened women who remain unreached by clinician-based cervical cancer screening and vaginal self-sampling. Yet, the...

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Bibliographic Details
Main Authors: Mette Tranberg, Severien Van Keer, Jørgen Skov Jensen, Pia Nørgaard, Line Winther Gustafson, Anne Hammer, Pinar Bor, Karen Omann Binderup, Christina Blach, Alex Vorsters
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Medicine
Subjects:
Cervical cancer screening
Mass screening
HrHPV DNA testing
Urinary hrHPV testing
Uterine cervical dysplasia
Sensitivity and specificity
Online Access:https://doi.org/10.1186/s12916-025-04149-0
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