HMGB1 regulates the activation of dendritic cells and CD4+ T cell responses through the modulation of autophagy in bleomycin-induced pulmonary fibrosis

HMGB1 regulates the activation of dendritic cells and CD4+ T cell responses through the modulation of autophagy in bleomycin-induced pulmonary fibrosis

Background: The role of HMGB1 in inflammation and autophagy has garnered increasing attention; however, its impact on the activation of dendritic cells (DCs) and autophagy remains unclear. This study aims to explore the effects of HMGB1 on DC activation, autophagy, and its influence on CD4+ T cell r...

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Bibliographic Details
Main Authors: Xiuhua Liu, Xinghui Song, Guangting Li, Yuping Zhang, Nina Liu, Kaijiang Tang, Hongyan Du, Ligang Jie
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Immunobiology
Subjects:
Bleomycin
Pulmonary fibrosis
HMGB1
Dendritic cells
Autophagy
CD4+ T cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298525000403
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