Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

Parkinson’s disease is the second most common progressive neurodegenerative disorder, and few reliable biomarkers are available to track disease progression. The proteins, DNA, mRNA, and lipids carried by exosomes reflect intracellular changes, and thus can serve as biomarkers for a variety of condi...

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Bibliographic Details
Main Authors: Yuan Zhao, Yidan Zhang, Xin Liu, Jian Zhang, Ya Gao, Shuyue Li, Cui Chang, Xiang Liu, Guofeng Yang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-10-01
Series:Neural Regeneration Research
Subjects:
biomarker
diagnosis
exosomes
n-acetyl-alpha-glucosaminidase
parkinson’s disease
proteomic
α-synuclein
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-23-01500
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