Primary Cardiac Angiosarcoma: A Fatal Disease
A 42-year-old man with a cardiac tamponade underwent an urgent pericardiotomy that showed tumoral tissue, covering the surface of the right atrium. The tumor was then partially excised, and the histological examination revealed the presence of a moderately-differentiated angiosarcoma. The patient wa...
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Wiley
2009-01-01
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Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2009/591512 |
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author | L. Antonuzzo V. Rotella F. Mazzoni L. Doni D. Bianchini F. Garbini V. Maio F. Di Costanzo |
author_facet | L. Antonuzzo V. Rotella F. Mazzoni L. Doni D. Bianchini F. Garbini V. Maio F. Di Costanzo |
author_sort | L. Antonuzzo |
collection | DOAJ |
description | A 42-year-old man with a cardiac tamponade underwent an urgent pericardiotomy that showed tumoral tissue, covering the surface of the right atrium. The tumor was then partially excised, and the histological examination revealed the presence of a moderately-differentiated angiosarcoma. The patient was then referred to the oncology unit and scheduled for a chemotherapy schedule including Epirubicin (60 mg/m2, on days 1 and 2) plus Ifosfamide (2000 mg/m2, on days 1 to 3) and Uromitexan (2000 mg/m2 at hours 0, 4, 8 after IFO). All drugs were administered every three weeks. After two cycles, a restaging work-up revealed a partial remission. The treatment was continued for another two cycles. A new evaluation by cardiac MRI evidenced a local and distant (lung) progression of disease. The patient died after three months. This paper confirms that cardiac angiosarcoma is a fatal disease, and the prognosis is usually 6–11 months from time of diagnosis. |
format | Article |
id | doaj-art-e6245ee923834d518655d1138c25453b |
institution | Kabale University |
issn | 1687-9627 1687-9635 |
language | English |
publishDate | 2009-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Medicine |
spelling | doaj-art-e6245ee923834d518655d1138c25453b2025-02-03T01:33:29ZengWileyCase Reports in Medicine1687-96271687-96352009-01-01200910.1155/2009/591512591512Primary Cardiac Angiosarcoma: A Fatal DiseaseL. Antonuzzo0V. Rotella1F. Mazzoni2L. Doni3D. Bianchini4F. Garbini5V. Maio6F. Di Costanzo7Oncologia Medica, Azienda Ospedale Universitaria Careggi, Viale Pieraccini 17, 50139 Firenze, ItalyOncologia Medica, Azienda Ospedale Universitaria Careggi, Viale Pieraccini 17, 50139 Firenze, ItalyOncologia Medica, Azienda Ospedale Universitaria Careggi, Viale Pieraccini 17, 50139 Firenze, ItalyOncologia Medica, Azienda Ospedale Universitaria Careggi, Viale Pieraccini 17, 50139 Firenze, ItalyOncologia Medica, Azienda Ospedale Universitaria Careggi, Viale Pieraccini 17, 50139 Firenze, ItalyDipartimento di Patologia Umana ed Oncologia, Azienda Ospedale Universitaria Careggi, Viale Pieraccini 17, 50139 Firenze, ItalyDipartimento di Patologia Umana ed Oncologia, Azienda Ospedale Universitaria Careggi, Viale Pieraccini 17, 50139 Firenze, ItalyOncologia Medica, Azienda Ospedale Universitaria Careggi, Viale Pieraccini 17, 50139 Firenze, ItalyA 42-year-old man with a cardiac tamponade underwent an urgent pericardiotomy that showed tumoral tissue, covering the surface of the right atrium. The tumor was then partially excised, and the histological examination revealed the presence of a moderately-differentiated angiosarcoma. The patient was then referred to the oncology unit and scheduled for a chemotherapy schedule including Epirubicin (60 mg/m2, on days 1 and 2) plus Ifosfamide (2000 mg/m2, on days 1 to 3) and Uromitexan (2000 mg/m2 at hours 0, 4, 8 after IFO). All drugs were administered every three weeks. After two cycles, a restaging work-up revealed a partial remission. The treatment was continued for another two cycles. A new evaluation by cardiac MRI evidenced a local and distant (lung) progression of disease. The patient died after three months. This paper confirms that cardiac angiosarcoma is a fatal disease, and the prognosis is usually 6–11 months from time of diagnosis.http://dx.doi.org/10.1155/2009/591512 |
spellingShingle | L. Antonuzzo V. Rotella F. Mazzoni L. Doni D. Bianchini F. Garbini V. Maio F. Di Costanzo Primary Cardiac Angiosarcoma: A Fatal Disease Case Reports in Medicine |
title | Primary Cardiac Angiosarcoma: A Fatal Disease |
title_full | Primary Cardiac Angiosarcoma: A Fatal Disease |
title_fullStr | Primary Cardiac Angiosarcoma: A Fatal Disease |
title_full_unstemmed | Primary Cardiac Angiosarcoma: A Fatal Disease |
title_short | Primary Cardiac Angiosarcoma: A Fatal Disease |
title_sort | primary cardiac angiosarcoma a fatal disease |
url | http://dx.doi.org/10.1155/2009/591512 |
work_keys_str_mv | AT lantonuzzo primarycardiacangiosarcomaafataldisease AT vrotella primarycardiacangiosarcomaafataldisease AT fmazzoni primarycardiacangiosarcomaafataldisease AT ldoni primarycardiacangiosarcomaafataldisease AT dbianchini primarycardiacangiosarcomaafataldisease AT fgarbini primarycardiacangiosarcomaafataldisease AT vmaio primarycardiacangiosarcomaafataldisease AT fdicostanzo primarycardiacangiosarcomaafataldisease |