Transarterial chemoembolization plus apatinib for unresectable hepatocellular carcinoma: a multicenter, randomized, open-label, phase III trial

Transarterial chemoembolization plus apatinib for unresectable hepatocellular carcinoma: a multicenter, randomized, open-label, phase III trial

Abstract Background This study aimed to assess the efficacy and safety of transarterial chemoembolization (TACE) in combination with apatinib (TACE-apatinib) for patients with unresectable hepatocellular carcinoma (HCC). Methods This study was a multicenter, randomized, open-label, prospective, phas...

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Main Authors: Xue-Feng Kan, Bin Liang, Xiao-Lin Zhang, Lei Yu, Yao-Chang Luo, Shi Zhou, Rui-Bao Liu, Guo-Hui Xu, Hai-Liang Li, Zheng-Yin Liao, Hua Xiang, Wei Lu, Lin-Feng Xu, Yi-Long Ma, Xiang-Wen Xia, Kun Qian, Xiang-Jun Dong, Fu Xiong, Song-Lin Song, Chang Zhao, Ming Huang, Chuan-Sheng Zheng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Medicine
Subjects:
Transarterial chemoembolization
Apatinib
Hepatocellular carcinoma
Progression free survival
Online Access:https://doi.org/10.1186/s12916-025-04159-y
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