Comparative performance of tuberculin and defined-antigen cocktails for detecting bovine tuberculosis in BCG-vaccinated cattle in natural settings

Comparative performance of tuberculin and defined-antigen cocktails for detecting bovine tuberculosis in BCG-vaccinated cattle in natural settings

Abstract Bovine tuberculosis (bTB) is a threat to cattle health and public safety. The current control programs are hampered by wildlife reservoirs and socioeconomic barriers. Vaccinating cattle with Bacillus Calmette-Guérin (BCG) effectively reduces transmission, offering a potential solution for c...

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Main Authors: Abebe Fromsa, Andrew J. K. Conlan, Sreenidhi Srinivasan, Balako Gumi, Wegene Bedada, Miserach Zeleke, Dawit Worku, Matios Lakew, Biniam Tadesse, Berecha Bayissa, Asegedech Sirak, Musse Girma Abdela, Getnet Abie Mekonnen, Tesfaye Chibssa, Maroudam Veerasami, Gareth J. Jones, H. Martin Vordermeier, Nick Juleff, James L. N. Wood, Gobena Ameni, Vivek Kapur
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
BCG vaccination
Bovine tuberculosis
Defined antigen cocktails
Tuberculin
IGRA and skin tests
Online Access:https://doi.org/10.1038/s41598-025-85389-1
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