Peritonitis and splenitis caused by MAC-infection in an immunosuppressed patient

Primary (hematogenic) peritonitis caused by non-tuberculosis mycobacteria is extremely rare in the clinical practice. The main number of reported episodes of primary intraabdominal infection is associated with M. tuberculosis and the development of granulomatous inflammation of the peritoneum visual...

Full description

Saved in:
Bibliographic Details
Main Authors: D. V. Plotkin, M. N. Reshetnikov, M. V. Sinitsyn, Yu. R. Zyuzya
Format: Article
Language:Russian
Published: Journal Infectology 2021-10-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/1252
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849387760288268288
author D. V. Plotkin
M. N. Reshetnikov
M. V. Sinitsyn
Yu. R. Zyuzya
author_facet D. V. Plotkin
M. N. Reshetnikov
M. V. Sinitsyn
Yu. R. Zyuzya
author_sort D. V. Plotkin
collection DOAJ
description Primary (hematogenic) peritonitis caused by non-tuberculosis mycobacteria is extremely rare in the clinical practice. The main number of reported episodes of primary intraabdominal infection is associated with M. tuberculosis and the development of granulomatous inflammation of the peritoneum visually similar to carcinomatosis. The vast majority of reports of peritonitis associated with non-tuberculosis mycobacteria are interlinked with chronic peritoneal dialysis or foreign bodies of the abdominal cavity, when an infection is carried out by the contact through a dialysis catheter, prosthesis or a gastric banding device. The article describes a clinical case of peritonitis and splenitis caused by M. avium with hematogenic spread of infection from the primary pulmonary focus in a young patient with immunosuppression. Diagnosis of such peritonitis at the preoperative stage is extremely difficult due to the similarity of symptoms with atypical appendicitis or infected ascites. The intraoperative picture also did not allow us to assume a mycobacterial etiology of the process, and the absence of a focal point of peritonitis made it necessary to thoroughly understand the situation. Only a peritoneal biopsy and a complete laboratory examination of exudate allowed us to verify the diagnosis, to understand the pathogenetic mechanisms of the disease and to start a timely etiotropic therapy.
format Article
id doaj-art-e617fab8e71e4aa3b0b342d3221c7361
institution Kabale University
issn 2072-6732
language Russian
publishDate 2021-10-01
publisher Journal Infectology
record_format Article
series Журнал инфектологии
spelling doaj-art-e617fab8e71e4aa3b0b342d3221c73612025-08-20T03:44:24ZrusJournal InfectologyЖурнал инфектологии2072-67322021-10-0113313514210.22625/2072-6732-2021-13-3-135-142946Peritonitis and splenitis caused by MAC-infection in an immunosuppressed patientD. V. Plotkin0M. N. Reshetnikov1M. V. Sinitsyn2Yu. R. Zyuzya3Moscow Research and Clinical Centre for Tuberculosis Control; Russian National Research Medical University named after N.I. PirogovMoscow Research and Clinical Centre for Tuberculosis ControlMoscow Research and Clinical Centre for Tuberculosis ControlClinical infectious diseases Hospital № 2Primary (hematogenic) peritonitis caused by non-tuberculosis mycobacteria is extremely rare in the clinical practice. The main number of reported episodes of primary intraabdominal infection is associated with M. tuberculosis and the development of granulomatous inflammation of the peritoneum visually similar to carcinomatosis. The vast majority of reports of peritonitis associated with non-tuberculosis mycobacteria are interlinked with chronic peritoneal dialysis or foreign bodies of the abdominal cavity, when an infection is carried out by the contact through a dialysis catheter, prosthesis or a gastric banding device. The article describes a clinical case of peritonitis and splenitis caused by M. avium with hematogenic spread of infection from the primary pulmonary focus in a young patient with immunosuppression. Diagnosis of such peritonitis at the preoperative stage is extremely difficult due to the similarity of symptoms with atypical appendicitis or infected ascites. The intraoperative picture also did not allow us to assume a mycobacterial etiology of the process, and the absence of a focal point of peritonitis made it necessary to thoroughly understand the situation. Only a peritoneal biopsy and a complete laboratory examination of exudate allowed us to verify the diagnosis, to understand the pathogenetic mechanisms of the disease and to start a timely etiotropic therapy.https://journal.niidi.ru/jofin/article/view/1252mac-infectionnon-tuberculosis mycobacteriosisperitonitissplenitishiv-infectionimmunosuppression
spellingShingle D. V. Plotkin
M. N. Reshetnikov
M. V. Sinitsyn
Yu. R. Zyuzya
Peritonitis and splenitis caused by MAC-infection in an immunosuppressed patient
Журнал инфектологии
mac-infection
non-tuberculosis mycobacteriosis
peritonitis
splenitis
hiv-infection
immunosuppression
title Peritonitis and splenitis caused by MAC-infection in an immunosuppressed patient
title_full Peritonitis and splenitis caused by MAC-infection in an immunosuppressed patient
title_fullStr Peritonitis and splenitis caused by MAC-infection in an immunosuppressed patient
title_full_unstemmed Peritonitis and splenitis caused by MAC-infection in an immunosuppressed patient
title_short Peritonitis and splenitis caused by MAC-infection in an immunosuppressed patient
title_sort peritonitis and splenitis caused by mac infection in an immunosuppressed patient
topic mac-infection
non-tuberculosis mycobacteriosis
peritonitis
splenitis
hiv-infection
immunosuppression
url https://journal.niidi.ru/jofin/article/view/1252
work_keys_str_mv AT dvplotkin peritonitisandsplenitiscausedbymacinfectioninanimmunosuppressedpatient
AT mnreshetnikov peritonitisandsplenitiscausedbymacinfectioninanimmunosuppressedpatient
AT mvsinitsyn peritonitisandsplenitiscausedbymacinfectioninanimmunosuppressedpatient
AT yurzyuzya peritonitisandsplenitiscausedbymacinfectioninanimmunosuppressedpatient