Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics
The aim of review. To present up-to-date data on etiology, pathogenesis, clinical presentation and diagnostics of cardiac achalasia.Key points. Cardiac achalasia represents primary esophageal motor disease with involvement of myenteric plexus. Basic symptoms of achalasia include dysphagia, regurgita...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Gastro LLC
2014-12-01
|
| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| Subjects: | |
| Online Access: | https://www.gastro-j.ru/jour/article/view/1150 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823860090017415168 |
|---|---|
| author | Yu. V. Yevsyutina O. A. Storonova A. S. Trukhmanov V. T. Ivashkin |
| author_facet | Yu. V. Yevsyutina O. A. Storonova A. S. Trukhmanov V. T. Ivashkin |
| author_sort | Yu. V. Yevsyutina |
| collection | DOAJ |
| description | The aim of review. To present up-to-date data on etiology, pathogenesis, clinical presentation and diagnostics of cardiac achalasia.Key points. Cardiac achalasia represents primary esophageal motor disease with involvement of myenteric plexus. Basic symptoms of achalasia include dysphagia, regurgitation, chest pain and weight loss. Esophageal manometry which allows to evaluate resting pressure and relaxation phenomenon of the lower esophageal sphincter and peristaltic activity of distal part of the esophagus is the «gold standard» of diagnostics. Genetic, autoimmune and infectious theories are considered for disease etiology.Conclusion. For the present moment pathogenesis, clinical presentation and diagnostics methods of cardiac achalasia are investigated in detail, however etiology of disease remains unknown, despite of centuries-old history. The major attention is drawn to autoimmune theory which requires further investigations. |
| format | Article |
| id | doaj-art-e61232c86c2d4d82981a970746130aae |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2014-12-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-e61232c86c2d4d82981a970746130aae2025-02-10T16:14:39ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732014-12-01246412745Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnosticsYu. V. Yevsyutina0O. A. Storonova1A. S. Trukhmanov2V. T. Ivashkin3State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of the Russian FederationState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of the Russian FederationState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of the Russian FederationState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of the Russian FederationThe aim of review. To present up-to-date data on etiology, pathogenesis, clinical presentation and diagnostics of cardiac achalasia.Key points. Cardiac achalasia represents primary esophageal motor disease with involvement of myenteric plexus. Basic symptoms of achalasia include dysphagia, regurgitation, chest pain and weight loss. Esophageal manometry which allows to evaluate resting pressure and relaxation phenomenon of the lower esophageal sphincter and peristaltic activity of distal part of the esophagus is the «gold standard» of diagnostics. Genetic, autoimmune and infectious theories are considered for disease etiology.Conclusion. For the present moment pathogenesis, clinical presentation and diagnostics methods of cardiac achalasia are investigated in detail, however etiology of disease remains unknown, despite of centuries-old history. The major attention is drawn to autoimmune theory which requires further investigations.https://www.gastro-j.ru/jour/article/view/1150cardiac achalasiaautoantibodiesdysphagia |
| spellingShingle | Yu. V. Yevsyutina O. A. Storonova A. S. Trukhmanov V. T. Ivashkin Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics Российский журнал гастроэнтерологии, гепатологии, колопроктологии cardiac achalasia autoantibodies dysphagia |
| title | Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics |
| title_full | Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics |
| title_fullStr | Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics |
| title_full_unstemmed | Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics |
| title_short | Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics |
| title_sort | cardiac achalasia modern concepts on etiology pathogenesis clinical presentation and diagnostics |
| topic | cardiac achalasia autoantibodies dysphagia |
| url | https://www.gastro-j.ru/jour/article/view/1150 |
| work_keys_str_mv | AT yuvyevsyutina cardiacachalasiamodernconceptsonetiologypathogenesisclinicalpresentationanddiagnostics AT oastoronova cardiacachalasiamodernconceptsonetiologypathogenesisclinicalpresentationanddiagnostics AT astrukhmanov cardiacachalasiamodernconceptsonetiologypathogenesisclinicalpresentationanddiagnostics AT vtivashkin cardiacachalasiamodernconceptsonetiologypathogenesisclinicalpresentationanddiagnostics |