Pyrimidine Azepine Targets the Plasmodium bc1 Complex and Displays Multistage Antimalarial Activity
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2024-10-01
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| Series: | JACS Au |
| Online Access: | https://doi.org/10.1021/jacsau.4c00674 |
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| author | Juliana Calit Surendra K. Prajapati Ernest D. Benavente Jessica E. Araújo Bingbing Deng Kazutoyo Miura Yasmin Annunciato Igor M. R. Moura Miho Usui Jansen F. Medeiros Carolina H. Andrade Sabrina Silva-Mendonça Anton Simeonov Richard T. Eastman Carole A. Long Maisa da Silva Araujo Kim C. Williamson Anna Caroline C. Aguiar Daniel Y. Bargieri |
| author_facet | Juliana Calit Surendra K. Prajapati Ernest D. Benavente Jessica E. Araújo Bingbing Deng Kazutoyo Miura Yasmin Annunciato Igor M. R. Moura Miho Usui Jansen F. Medeiros Carolina H. Andrade Sabrina Silva-Mendonça Anton Simeonov Richard T. Eastman Carole A. Long Maisa da Silva Araujo Kim C. Williamson Anna Caroline C. Aguiar Daniel Y. Bargieri |
| author_sort | Juliana Calit |
| collection | DOAJ |
| format | Article |
| id | doaj-art-e61187396b05419984437594f79932dd |
| institution | DOAJ |
| issn | 2691-3704 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | JACS Au |
| spelling | doaj-art-e61187396b05419984437594f79932dd2025-08-20T02:44:36ZengAmerican Chemical SocietyJACS Au2691-37042024-10-014103942395210.1021/jacsau.4c00674Pyrimidine Azepine Targets the Plasmodium bc1 Complex and Displays Multistage Antimalarial ActivityJuliana Calit0Surendra K. Prajapati1Ernest D. Benavente2Jessica E. Araújo3Bingbing Deng4Kazutoyo Miura5Yasmin Annunciato6Igor M. R. Moura7Miho Usui8Jansen F. Medeiros9Carolina H. Andrade10Sabrina Silva-Mendonça11Anton Simeonov12Richard T. Eastman13Carole A. Long14Maisa da Silva Araujo15Kim C. Williamson16Anna Caroline C. Aguiar17Daniel Y. Bargieri18Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, BrazilDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United StatesLaboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, The NetherlandsPlataforma de Produção e Infecção de Vetores da Malária−PIVEM, Laboratório de Entomologia, Fundação Oswaldo Cruz-Fiocruz Rondônia, Porto Velho, RO, BrazilLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United StatesLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United StatesDepartment of Bioscience, Federal University of São Paulo, São Paulo, SP, BrazilInstitute of Physics of São Carlos, University of São Paulo, São Carlos, SP, BrazilDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United StatesPlataforma de Produção e Infecção de Vetores da Malária−PIVEM, Laboratório de Entomologia, Fundação Oswaldo Cruz-Fiocruz Rondônia, Porto Velho, RO, BrazilLabMol−Laboratory for Molecular Modeling and Drug Design−Faculty of Pharmacy, Federal University of Goias, Goiania, GO, BrazilLabMol−Laboratory for Molecular Modeling and Drug Design−Faculty of Pharmacy, Federal University of Goias, Goiania, GO, BrazilDivision of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United StatesDivision of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United StatesLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United StatesPlataforma de Produção e Infecção de Vetores da Malária−PIVEM, Laboratório de Entomologia, Fundação Oswaldo Cruz-Fiocruz Rondônia, Porto Velho, RO, BrazilDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United StatesDepartment of Bioscience, Federal University of São Paulo, São Paulo, SP, BrazilDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazilhttps://doi.org/10.1021/jacsau.4c00674 |
| spellingShingle | Juliana Calit Surendra K. Prajapati Ernest D. Benavente Jessica E. Araújo Bingbing Deng Kazutoyo Miura Yasmin Annunciato Igor M. R. Moura Miho Usui Jansen F. Medeiros Carolina H. Andrade Sabrina Silva-Mendonça Anton Simeonov Richard T. Eastman Carole A. Long Maisa da Silva Araujo Kim C. Williamson Anna Caroline C. Aguiar Daniel Y. Bargieri Pyrimidine Azepine Targets the Plasmodium bc1 Complex and Displays Multistage Antimalarial Activity JACS Au |
| title | Pyrimidine Azepine Targets the Plasmodium bc1 Complex and Displays Multistage Antimalarial Activity |
| title_full | Pyrimidine Azepine Targets the Plasmodium bc1 Complex and Displays Multistage Antimalarial Activity |
| title_fullStr | Pyrimidine Azepine Targets the Plasmodium bc1 Complex and Displays Multistage Antimalarial Activity |
| title_full_unstemmed | Pyrimidine Azepine Targets the Plasmodium bc1 Complex and Displays Multistage Antimalarial Activity |
| title_short | Pyrimidine Azepine Targets the Plasmodium bc1 Complex and Displays Multistage Antimalarial Activity |
| title_sort | pyrimidine azepine targets the plasmodium bc1 complex and displays multistage antimalarial activity |
| url | https://doi.org/10.1021/jacsau.4c00674 |
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