Spectral Properties and Biological Activities of Binuclear Mixed-Metal Bridged Thiocyanate Complexes Containing Schiff Bases Derived from Isatin

This study introduces two novel Schiff base ligands synthesized through the condensation of isatin with primary amines. These ligands were characterized using infrared (IR), ultraviolet-visible (UV-Vis) spectroscopy, mass spectrometry, and elemental analysis. The ligands were further treated with te...

Full description

Saved in:
Bibliographic Details
Main Authors: Adyan Hameed Jasim, Mouayed Yousif Kadhum, Sanaa Qasem Badr
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Engineering Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4591/59/1/237
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850204475716796416
author Adyan Hameed Jasim
Mouayed Yousif Kadhum
Sanaa Qasem Badr
author_facet Adyan Hameed Jasim
Mouayed Yousif Kadhum
Sanaa Qasem Badr
author_sort Adyan Hameed Jasim
collection DOAJ
description This study introduces two novel Schiff base ligands synthesized through the condensation of isatin with primary amines. These ligands were characterized using infrared (IR), ultraviolet-visible (UV-Vis) spectroscopy, mass spectrometry, and elemental analysis. The ligands were further treated with tetrathiocyanate in a 1:1 molar ratio to yield binuclear mixed-metal monomeric bridged complexes of the form LMCd(SCN)<sub>4</sub>, where M represents Co(II) or Ni(II). Various spectral techniques and magnetic susceptibility measurements were employed for the identification of these complexes. The findings revealed that all the complexes possessed a coordination number of four and exhibited non-electrolytic behavior. Additionally, the cobalt complexes demonstrated paramagnetic properties, whereas the nickel complexes were diamagnetic. The antimicrobial efficacy of the Schiff base ligands and their complexes was also evaluated against selected microorganisms, revealing significant antimicrobial activities.
format Article
id doaj-art-e60f69b92cf64f6caacc55eb31052aea
institution OA Journals
issn 2673-4591
language English
publishDate 2024-03-01
publisher MDPI AG
record_format Article
series Engineering Proceedings
spelling doaj-art-e60f69b92cf64f6caacc55eb31052aea2025-08-20T02:11:17ZengMDPI AGEngineering Proceedings2673-45912024-03-0159123710.3390/engproc2023059237Spectral Properties and Biological Activities of Binuclear Mixed-Metal Bridged Thiocyanate Complexes Containing Schiff Bases Derived from IsatinAdyan Hameed Jasim0Mouayed Yousif Kadhum1Sanaa Qasem Badr2Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah 61004, IraqDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah 61004, IraqDepartment of Natural Marine Sciences, College of Marine Sciences, University of Basrah, Basrah 61004, IraqThis study introduces two novel Schiff base ligands synthesized through the condensation of isatin with primary amines. These ligands were characterized using infrared (IR), ultraviolet-visible (UV-Vis) spectroscopy, mass spectrometry, and elemental analysis. The ligands were further treated with tetrathiocyanate in a 1:1 molar ratio to yield binuclear mixed-metal monomeric bridged complexes of the form LMCd(SCN)<sub>4</sub>, where M represents Co(II) or Ni(II). Various spectral techniques and magnetic susceptibility measurements were employed for the identification of these complexes. The findings revealed that all the complexes possessed a coordination number of four and exhibited non-electrolytic behavior. Additionally, the cobalt complexes demonstrated paramagnetic properties, whereas the nickel complexes were diamagnetic. The antimicrobial efficacy of the Schiff base ligands and their complexes was also evaluated against selected microorganisms, revealing significant antimicrobial activities.https://www.mdpi.com/2673-4591/59/1/237isatinthiocyanatespectral analysisSchiff basebinuclear complexesbiological activity
spellingShingle Adyan Hameed Jasim
Mouayed Yousif Kadhum
Sanaa Qasem Badr
Spectral Properties and Biological Activities of Binuclear Mixed-Metal Bridged Thiocyanate Complexes Containing Schiff Bases Derived from Isatin
Engineering Proceedings
isatin
thiocyanate
spectral analysis
Schiff base
binuclear complexes
biological activity
title Spectral Properties and Biological Activities of Binuclear Mixed-Metal Bridged Thiocyanate Complexes Containing Schiff Bases Derived from Isatin
title_full Spectral Properties and Biological Activities of Binuclear Mixed-Metal Bridged Thiocyanate Complexes Containing Schiff Bases Derived from Isatin
title_fullStr Spectral Properties and Biological Activities of Binuclear Mixed-Metal Bridged Thiocyanate Complexes Containing Schiff Bases Derived from Isatin
title_full_unstemmed Spectral Properties and Biological Activities of Binuclear Mixed-Metal Bridged Thiocyanate Complexes Containing Schiff Bases Derived from Isatin
title_short Spectral Properties and Biological Activities of Binuclear Mixed-Metal Bridged Thiocyanate Complexes Containing Schiff Bases Derived from Isatin
title_sort spectral properties and biological activities of binuclear mixed metal bridged thiocyanate complexes containing schiff bases derived from isatin
topic isatin
thiocyanate
spectral analysis
Schiff base
binuclear complexes
biological activity
url https://www.mdpi.com/2673-4591/59/1/237
work_keys_str_mv AT adyanhameedjasim spectralpropertiesandbiologicalactivitiesofbinuclearmixedmetalbridgedthiocyanatecomplexescontainingschiffbasesderivedfromisatin
AT mouayedyousifkadhum spectralpropertiesandbiologicalactivitiesofbinuclearmixedmetalbridgedthiocyanatecomplexescontainingschiffbasesderivedfromisatin
AT sanaaqasembadr spectralpropertiesandbiologicalactivitiesofbinuclearmixedmetalbridgedthiocyanatecomplexescontainingschiffbasesderivedfromisatin