Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy?
Introduction: This study aims to show the bacteriologic picture of acute prostatitis and bacteremia caused by infective agent after transrectal ultrasound-guided prostate biopsy (TRUSBx) and to determine the resistance rates of the infections in patients undergoing transrectal biopsy and to guide p...
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The Journal of Infection in Developing Countries
2024-04-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/18209 |
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| author | Adalet Altunsoy Şeref Coşer Nizamettin Kemirtlek Ibrahim Can Aykanat Melih Balci Hürrem Bodur Altuğ Tuncel |
| author_facet | Adalet Altunsoy Şeref Coşer Nizamettin Kemirtlek Ibrahim Can Aykanat Melih Balci Hürrem Bodur Altuğ Tuncel |
| author_sort | Adalet Altunsoy |
| collection | DOAJ |
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Introduction: This study aims to show the bacteriologic picture of acute prostatitis and bacteremia caused by infective agent after transrectal ultrasound-guided prostate biopsy (TRUSBx) and to determine the resistance rates of the infections in patients undergoing transrectal biopsy and to guide prophylaxis approach before biopsy.
Methodology: The retrospective data of 935 patients who underwent TRUSBx between January 2010 to January 2019 were reviewed. Pre-biopsy urine cultures and antimicrobial susceptibility were obtained. Subsequently, patients admitted to the hospital with any complaint after biopsy were examined for severe infection complications.
Results: Of the 430 (61.7%) patients who underwent urine culture before the procedure, 45 (10.5%) had growth; 30 (66.7%) of the growing microorganisms were Escherichia coli. Twenty (44.4%) of all Gram-negative agents in pre-biopsy urine culture were susceptible to quinolone. Post TRUSBx bacteremia was present in 18.2%, urinary system infection in 83.6%, and hospitalization in 61.8% of 55 patients who were admitted to the hospital. In the isolated gram-negative microorganisms, fluoroquinolones resistance in urinary system infections was seen in 40% and bacteremia was seen in 70% of the cases. ESBL-producing Gram-negative bacteria were determined in 40% of infections in blood and 38.5% of urinary system infections in the post biopsy period in the current study.
Conclusions: These high antibiotic resistance rates suggest that we better review our pre-procedure prophylaxis approaches.
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| format | Article |
| id | doaj-art-e60d5df730cc4008a8c99df560e84ce8 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | The Journal of Infection in Developing Countries |
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| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-e60d5df730cc4008a8c99df560e84ce82025-08-20T02:16:06ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802024-04-01180410.3855/jidc.18209Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy?Adalet Altunsoy0Şeref Coşer1Nizamettin Kemirtlek2Ibrahim Can Aykanat3Melih Balci4Hürrem Bodur5Altuğ Tuncel6University of Health Science, Ankara City Hospital, Infectious Diseases and Clinical Microbiology. Ankara, TurkeyDepartment of Urology, University of Health Sciences, School of Medicine, Ankara City Hospital, Ankara, TurkeyAnkara City Hospital, Infectious Diseases and Clinical Microbiology. Ankara, TurkeyDepartment of Urology, Koç University Hospital, İstanbul, TurkeyDepartment of Urology, University of Health Sciences, School of Medicine, Ankara City Hospital, Ankara, TurkeyUniversity of Health Science, Ankara City Hospital, Infectious Diseases and Clinical Microbiology. Ankara, TurkeyDepartment of Urology, University of Health Sciences, School of Medicine, Ankara City Hospital, Ankara, Turkey Introduction: This study aims to show the bacteriologic picture of acute prostatitis and bacteremia caused by infective agent after transrectal ultrasound-guided prostate biopsy (TRUSBx) and to determine the resistance rates of the infections in patients undergoing transrectal biopsy and to guide prophylaxis approach before biopsy. Methodology: The retrospective data of 935 patients who underwent TRUSBx between January 2010 to January 2019 were reviewed. Pre-biopsy urine cultures and antimicrobial susceptibility were obtained. Subsequently, patients admitted to the hospital with any complaint after biopsy were examined for severe infection complications. Results: Of the 430 (61.7%) patients who underwent urine culture before the procedure, 45 (10.5%) had growth; 30 (66.7%) of the growing microorganisms were Escherichia coli. Twenty (44.4%) of all Gram-negative agents in pre-biopsy urine culture were susceptible to quinolone. Post TRUSBx bacteremia was present in 18.2%, urinary system infection in 83.6%, and hospitalization in 61.8% of 55 patients who were admitted to the hospital. In the isolated gram-negative microorganisms, fluoroquinolones resistance in urinary system infections was seen in 40% and bacteremia was seen in 70% of the cases. ESBL-producing Gram-negative bacteria were determined in 40% of infections in blood and 38.5% of urinary system infections in the post biopsy period in the current study. Conclusions: These high antibiotic resistance rates suggest that we better review our pre-procedure prophylaxis approaches. https://jidc.org/index.php/journal/article/view/18209Antibiotic resistancefluoroquinoloneprophylaxisprostate biopsy |
| spellingShingle | Adalet Altunsoy Şeref Coşer Nizamettin Kemirtlek Ibrahim Can Aykanat Melih Balci Hürrem Bodur Altuğ Tuncel Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy? Journal of Infection in Developing Countries Antibiotic resistance fluoroquinolone prophylaxis prostate biopsy |
| title | Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy? |
| title_full | Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy? |
| title_fullStr | Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy? |
| title_full_unstemmed | Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy? |
| title_short | Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy? |
| title_sort | should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy |
| topic | Antibiotic resistance fluoroquinolone prophylaxis prostate biopsy |
| url | https://jidc.org/index.php/journal/article/view/18209 |
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