Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in apple

Myo-inositol and its derivatives play important roles in the tolerance of higher plants to abiotic stresses, and myo-inositol-1-phosphate synthase (MIPS) is the rate-limiting enzyme in myo-inositol biosynthesis. In this study, we found that increased myo-inositol biosynthesis enhanced drought tolera...

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Main Authors: Ling-yu HU, Hong YUE, Jing-yun ZHANG, Yang-tian-su LI, Xiao-qing GONG, Kun ZHOU, Feng-wang MA
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-07-01
Series:Journal of Integrative Agriculture
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Online Access:http://www.sciencedirect.com/science/article/pii/S2095311921638224
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_version_ 1849248211078742016
author Ling-yu HU
Hong YUE
Jing-yun ZHANG
Yang-tian-su LI
Xiao-qing GONG
Kun ZHOU
Feng-wang MA
author_facet Ling-yu HU
Hong YUE
Jing-yun ZHANG
Yang-tian-su LI
Xiao-qing GONG
Kun ZHOU
Feng-wang MA
author_sort Ling-yu HU
collection DOAJ
description Myo-inositol and its derivatives play important roles in the tolerance of higher plants to abiotic stresses, and myo-inositol-1-phosphate synthase (MIPS) is the rate-limiting enzyme in myo-inositol biosynthesis. In this study, we found that increased myo-inositol biosynthesis enhanced drought tolerance in MdMIPS1-overexpressing apple lines under short-term progressive drought stress. The effect of myo-inositol appeared to be mediated by the increased accumulation of osmoprotectants such as glucose, sucrose, and proline, and by the increased activities of antioxidant enzymes that eliminate reactive oxygen species. Moreover, enhanced water-use efficiency (WUE) was observed in MdMIPS1-overexpressing apple lines under long-term moderate water deficit conditions that mimicked the water availability in the soil of the Loess Plateau. Enhanced WUE may have been associated with the synergistic regulation of osmotic balance and stomatal aperture mediated by increased myo-inositol biosynthesis. Taken together, our findings shed light on the positive effects of MdMIPS1-mediated myo-inositol biosynthesis on drought tolerance and WUE in apple.
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institution Kabale University
issn 2095-3119
language English
publishDate 2022-07-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Journal of Integrative Agriculture
spelling doaj-art-e5ee31062caa4a4d868dec0e279e46ce2025-08-20T03:57:59ZengKeAi Communications Co., Ltd.Journal of Integrative Agriculture2095-31192022-07-012171968198110.1016/S2095-3119(21)63822-4Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in appleLing-yu HU0Hong YUE1Jing-yun ZHANG2Yang-tian-su LI3Xiao-qing GONG4Kun ZHOU5Feng-wang MA6State Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling 712100, P.R.ChinaState Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling 712100, P.R.ChinaState Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling 712100, P.R.ChinaState Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling 712100, P.R.ChinaState Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling 712100, P.R.ChinaState Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling 712100, P.R.ChinaCorrespondence MA Feng-wang, Tel: +86-29-87082648; State Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling 712100, P.R.ChinaMyo-inositol and its derivatives play important roles in the tolerance of higher plants to abiotic stresses, and myo-inositol-1-phosphate synthase (MIPS) is the rate-limiting enzyme in myo-inositol biosynthesis. In this study, we found that increased myo-inositol biosynthesis enhanced drought tolerance in MdMIPS1-overexpressing apple lines under short-term progressive drought stress. The effect of myo-inositol appeared to be mediated by the increased accumulation of osmoprotectants such as glucose, sucrose, and proline, and by the increased activities of antioxidant enzymes that eliminate reactive oxygen species. Moreover, enhanced water-use efficiency (WUE) was observed in MdMIPS1-overexpressing apple lines under long-term moderate water deficit conditions that mimicked the water availability in the soil of the Loess Plateau. Enhanced WUE may have been associated with the synergistic regulation of osmotic balance and stomatal aperture mediated by increased myo-inositol biosynthesis. Taken together, our findings shed light on the positive effects of MdMIPS1-mediated myo-inositol biosynthesis on drought tolerance and WUE in apple.http://www.sciencedirect.com/science/article/pii/S2095311921638224appleMdMIPS1myo-inositolwater deficitdrought tolerancewater-use efficiency
spellingShingle Ling-yu HU
Hong YUE
Jing-yun ZHANG
Yang-tian-su LI
Xiao-qing GONG
Kun ZHOU
Feng-wang MA
Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in apple
Journal of Integrative Agriculture
apple
MdMIPS1
myo-inositol
water deficit
drought tolerance
water-use efficiency
title Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in apple
title_full Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in apple
title_fullStr Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in apple
title_full_unstemmed Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in apple
title_short Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in apple
title_sort overexpression of mdmips1 enhances drought tolerance and water use efficiency in apple
topic apple
MdMIPS1
myo-inositol
water deficit
drought tolerance
water-use efficiency
url http://www.sciencedirect.com/science/article/pii/S2095311921638224
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