ENALAPRIL MALEATE IN TREATMENT OF ARTERIAL HYPERTENSION IN PATIENTS WITH DIABETES MELLITUS
The study includes 25 patients with arterial hypertension (AH) and 25 patients with non-insulin dependent diabetes mellitus (NIDDM) combined with AH. All patients, at baseline and 2 weeks following treatment with enalapril maleate (Enam, Dr.Reddy’s Laborotories Ltd., India), general clinical examina...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2002-10-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1902 |
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| author | L. I. Katelnitskaya G. O. Trenyova |
| author_facet | L. I. Katelnitskaya G. O. Trenyova |
| author_sort | L. I. Katelnitskaya |
| collection | DOAJ |
| description | The study includes 25 patients with arterial hypertension (AH) and 25 patients with non-insulin dependent diabetes mellitus (NIDDM) combined with AH. All patients, at baseline and 2 weeks following treatment with enalapril maleate (Enam, Dr.Reddy’s Laborotories Ltd., India), general clinical examination as well as measurement of blood glucose, cholesterol, lipoproteins, triglycerides; conventional echo and evaluation of vasomotoric function of endothelium by D.S. Celermajer’s method. We have shown that even with blood pressure decreasing to the same levels, endothelium-dependent relaxation improved best in the group with NIDDM whereas LV diastolic function dynamics did not differ significantly; those changes having strong correlation to the levels of serum lipoproteins and triglycerides. The results suggest enalapril maleate not just a nephropotective measure in patients with AH and NIDDM, but also as a medication for heart protection in such patients. |
| format | Article |
| id | doaj-art-e5e4eba8e2b745269308dce1e4ce41a7 |
| institution | Kabale University |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2002-10-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-e5e4eba8e2b745269308dce1e4ce41a72025-08-20T03:43:44Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202002-10-010554591662ENALAPRIL MALEATE IN TREATMENT OF ARTERIAL HYPERTENSION IN PATIENTS WITH DIABETES MELLITUSL. I. Katelnitskaya0G. O. Trenyova1Ростовский государственный медицинский университет, г. Ростов-на-Дону, БСМП №1, г. ШахтыРостовский государственный медицинский университет, г. Ростов-на-Дону, БСМП №1, г. ШахтыThe study includes 25 patients with arterial hypertension (AH) and 25 patients with non-insulin dependent diabetes mellitus (NIDDM) combined with AH. All patients, at baseline and 2 weeks following treatment with enalapril maleate (Enam, Dr.Reddy’s Laborotories Ltd., India), general clinical examination as well as measurement of blood glucose, cholesterol, lipoproteins, triglycerides; conventional echo and evaluation of vasomotoric function of endothelium by D.S. Celermajer’s method. We have shown that even with blood pressure decreasing to the same levels, endothelium-dependent relaxation improved best in the group with NIDDM whereas LV diastolic function dynamics did not differ significantly; those changes having strong correlation to the levels of serum lipoproteins and triglycerides. The results suggest enalapril maleate not just a nephropotective measure in patients with AH and NIDDM, but also as a medication for heart protection in such patients.https://russjcardiol.elpub.ru/jour/article/view/1902arterial hypertensiondiabetes mellitusangiotensin converting ensime inhibitors |
| spellingShingle | L. I. Katelnitskaya G. O. Trenyova ENALAPRIL MALEATE IN TREATMENT OF ARTERIAL HYPERTENSION IN PATIENTS WITH DIABETES MELLITUS Российский кардиологический журнал arterial hypertension diabetes mellitus angiotensin converting ensime inhibitors |
| title | ENALAPRIL MALEATE IN TREATMENT OF ARTERIAL HYPERTENSION IN PATIENTS WITH DIABETES MELLITUS |
| title_full | ENALAPRIL MALEATE IN TREATMENT OF ARTERIAL HYPERTENSION IN PATIENTS WITH DIABETES MELLITUS |
| title_fullStr | ENALAPRIL MALEATE IN TREATMENT OF ARTERIAL HYPERTENSION IN PATIENTS WITH DIABETES MELLITUS |
| title_full_unstemmed | ENALAPRIL MALEATE IN TREATMENT OF ARTERIAL HYPERTENSION IN PATIENTS WITH DIABETES MELLITUS |
| title_short | ENALAPRIL MALEATE IN TREATMENT OF ARTERIAL HYPERTENSION IN PATIENTS WITH DIABETES MELLITUS |
| title_sort | enalapril maleate in treatment of arterial hypertension in patients with diabetes mellitus |
| topic | arterial hypertension diabetes mellitus angiotensin converting ensime inhibitors |
| url | https://russjcardiol.elpub.ru/jour/article/view/1902 |
| work_keys_str_mv | AT likatelnitskaya enalaprilmaleateintreatmentofarterialhypertensioninpatientswithdiabetesmellitus AT gotrenyova enalaprilmaleateintreatmentofarterialhypertensioninpatientswithdiabetesmellitus |