A comparative analysis of the antioxidant potential of watermelon (citrullus lanatus (thunb.)) mesocarp extract fractions evaluated by the DPPH method
Watermelon mesocarp contains bioactive compounds with antioxidant properties that hold significant scientific and industrial interest. Antioxidants from natural sources are increasingly explored for applications in food preservation, cosmetics, and pharmaceuticals due to their efficacy and safety. T...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2025-01-01
|
| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2025/03/bioconf_ichbs2025_01007.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832539716676747264 |
|---|---|
| author | Kusuma Ikhwan Yuda Yunas Afrah Febrina Dina Csupor Dezső Perdana Muhammad Iqbal Pratiwi Hening |
| author_facet | Kusuma Ikhwan Yuda Yunas Afrah Febrina Dina Csupor Dezső Perdana Muhammad Iqbal Pratiwi Hening |
| author_sort | Kusuma Ikhwan Yuda |
| collection | DOAJ |
| description | Watermelon mesocarp contains bioactive compounds with antioxidant properties that hold significant scientific and industrial interest. Antioxidants from natural sources are increasingly explored for applications in food preservation, cosmetics, and pharmaceuticals due to their efficacy and safety. This study aimed to identify fractions with strong antioxidant potential and explore their industrial applications. The crude extract was fractionated into water, ethyl acetate, and n-hexane fractions, and their antioxidant activity was evaluated using the DPPH method. The ethyl acetate fraction exhibited the strongest antioxidant activity, with an IC50 value of 7.68 ppm, which, while slightly less potent than ascorbic acid (IC50 = 4.09 ppm), demonstrated substantial free radical scavenging ability. This was followed by the water fraction (IC50 = 34.9 ppm), with the n-hexane fraction showing moderate activity (IC50 = 52.07 ppm). The ethyl acetate fraction of watermelon mesocarp extract demonstrated the strongest antioxidant activity, highlighting its potential for applications in food preservation and developing cosmetic formulations as a natural antioxidant source. |
| format | Article |
| id | doaj-art-e5df2638ba5644048b75462f75e1105e |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-e5df2638ba5644048b75462f75e1105e2025-02-05T10:42:50ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011520100710.1051/bioconf/202515201007bioconf_ichbs2025_01007A comparative analysis of the antioxidant potential of watermelon (citrullus lanatus (thunb.)) mesocarp extract fractions evaluated by the DPPH methodKusuma Ikhwan Yuda0Yunas Afrah1Febrina Dina2Csupor Dezső3Perdana Muhammad Iqbal4Pratiwi Hening5Pharmacy Study Program, Faculty of Health, Universitas Harapan BangsaPharmacy Study Program, Faculty of Health, Universitas Harapan BangsaPharmacy Study Program, Faculty of Health, Universitas Harapan BangsaInstitute of Clinical Pharmacy, University of SzegedDepartment of Biotechnology and Microbiology, Faculty of Science and Informatics, University of SzegedDepartment of Pharmacy, Faculty of Health Sciences, Universitas Jenderal SoedirmanWatermelon mesocarp contains bioactive compounds with antioxidant properties that hold significant scientific and industrial interest. Antioxidants from natural sources are increasingly explored for applications in food preservation, cosmetics, and pharmaceuticals due to their efficacy and safety. This study aimed to identify fractions with strong antioxidant potential and explore their industrial applications. The crude extract was fractionated into water, ethyl acetate, and n-hexane fractions, and their antioxidant activity was evaluated using the DPPH method. The ethyl acetate fraction exhibited the strongest antioxidant activity, with an IC50 value of 7.68 ppm, which, while slightly less potent than ascorbic acid (IC50 = 4.09 ppm), demonstrated substantial free radical scavenging ability. This was followed by the water fraction (IC50 = 34.9 ppm), with the n-hexane fraction showing moderate activity (IC50 = 52.07 ppm). The ethyl acetate fraction of watermelon mesocarp extract demonstrated the strongest antioxidant activity, highlighting its potential for applications in food preservation and developing cosmetic formulations as a natural antioxidant source.https://www.bio-conferences.org/articles/bioconf/pdf/2025/03/bioconf_ichbs2025_01007.pdf |
| spellingShingle | Kusuma Ikhwan Yuda Yunas Afrah Febrina Dina Csupor Dezső Perdana Muhammad Iqbal Pratiwi Hening A comparative analysis of the antioxidant potential of watermelon (citrullus lanatus (thunb.)) mesocarp extract fractions evaluated by the DPPH method BIO Web of Conferences |
| title | A comparative analysis of the antioxidant potential of watermelon (citrullus lanatus (thunb.)) mesocarp extract fractions evaluated by the DPPH method |
| title_full | A comparative analysis of the antioxidant potential of watermelon (citrullus lanatus (thunb.)) mesocarp extract fractions evaluated by the DPPH method |
| title_fullStr | A comparative analysis of the antioxidant potential of watermelon (citrullus lanatus (thunb.)) mesocarp extract fractions evaluated by the DPPH method |
| title_full_unstemmed | A comparative analysis of the antioxidant potential of watermelon (citrullus lanatus (thunb.)) mesocarp extract fractions evaluated by the DPPH method |
| title_short | A comparative analysis of the antioxidant potential of watermelon (citrullus lanatus (thunb.)) mesocarp extract fractions evaluated by the DPPH method |
| title_sort | comparative analysis of the antioxidant potential of watermelon citrullus lanatus thunb mesocarp extract fractions evaluated by the dpph method |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2025/03/bioconf_ichbs2025_01007.pdf |
| work_keys_str_mv | AT kusumaikhwanyuda acomparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT yunasafrah acomparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT febrinadina acomparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT csupordezso acomparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT perdanamuhammadiqbal acomparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT pratiwihening acomparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT kusumaikhwanyuda comparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT yunasafrah comparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT febrinadina comparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT csupordezso comparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT perdanamuhammadiqbal comparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod AT pratiwihening comparativeanalysisoftheantioxidantpotentialofwatermeloncitrulluslanatusthunbmesocarpextractfractionsevaluatedbythedpphmethod |