Isolation and characterization of DNA aptamers against the HlyE antigen of Salmonella Typhi

Isolation and characterization of DNA aptamers against the HlyE antigen of Salmonella Typhi

Abstract Aptamers have emerged as prominent ligands in clinical diagnostics because they provide various advantages over antibodies, such as quicker generation time, reduced manufacturing costs, minimal batch-to-batch variability, greater modifiability, and improved thermal stability. In the present...

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Main Authors: Mohamad Ahmad Najib, Anja Winter, Khairul Mohd Fadzli Mustaffa, Eugene Boon Beng Ong, Kasturi Selvam, Muhammad Fazli Khalid, Mohd Syafiq Awang, Asrulnizam Abd Manaf, Yazmin Bustami, Ismail Aziah
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
DNA aptamers
SELEX
HlyE antigen
Salmonella Typhi
Online Access:https://doi.org/10.1038/s41598-024-78685-9
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