Ossifying Fibroma with Co-existent Squamous Cell Carcinoma in Maxilla
INTRODUCTION: Ossifying fibroma is a rare benign bone lesion characterized by gradual development and asymptomatic presentation, typically affecting craniofacial bones in individuals, particularly females, during their second to fourth decades of life. The concurrent occurrence of ora...
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| Language: | English |
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The Association of Otolaryngologists of India, West Bengal
2025-03-01
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| Series: | Bengal Journal of Otolaryngology and Head Neck Surgery |
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| Online Access: | https://bjohns.in/journal23/index.php/bjohns/article/view/139 |
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| author | Navya Jacob Murali T V Indu M Amilu Elsa Varghese |
| author_facet | Navya Jacob Murali T V Indu M Amilu Elsa Varghese |
| author_sort | Navya Jacob |
| collection | DOAJ |
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INTRODUCTION: Ossifying fibroma is a rare benign bone lesion characterized by gradual development and asymptomatic presentation, typically affecting craniofacial bones in individuals, particularly females, during their second to fourth decades of life. The concurrent occurrence of oral squamous cell carcinoma (OSCC) with ossifying fibroma is exceedingly rare, with only one previous case reported.
CASE REPORT: We describe a 71-year-old male presenting with a gradually enlarging swelling in the oral cavity, initially treated five years prior for a mandibular fracture. Clinical examination revealed a large swelling in the right maxillary area, and imaging showed a radiolucent lesion with expansile characteristics. Histopathological analysis of the excised tissue initially suggested a benign fibro-osseous lesion. However, upon recurrence, a further biopsy revealed a coexistence of ossifying fibroma and well-differentiated squamous cell carcinoma in the previously affected palatal region.
DISCUSSION: The simultaneous presence of ossifying fibroma and OSCC is extremely rare. This case underscores the importance of thorough diagnostic evaluation and highlights potential associations between trauma and tumor development. Further research is needed to elucidate the relationship between these lesions and improve diagnostic and therapeutic approaches for such rare occurrences.
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| format | Article |
| id | doaj-art-e5ca0457f2644e8a98ee477941f93998 |
| institution | Kabale University |
| issn | 2395-2393 2395-2407 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | The Association of Otolaryngologists of India, West Bengal |
| record_format | Article |
| series | Bengal Journal of Otolaryngology and Head Neck Surgery |
| spelling | doaj-art-e5ca0457f2644e8a98ee477941f939982025-08-26T08:45:26ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-23932395-24072025-03-0132210.47210/bjohns.2024.v32i2.139Ossifying Fibroma with Co-existent Squamous Cell Carcinoma in MaxillaNavya Jacob0Murali T V1Indu M2Amilu Elsa Varghese3Government Medical College, Kottayam, KeralaGovernment Medical College, Kottayam, KeralaGoverment Dental College, Thrissur, KeralaGovernment Medical College, Kottayam, Kerala INTRODUCTION: Ossifying fibroma is a rare benign bone lesion characterized by gradual development and asymptomatic presentation, typically affecting craniofacial bones in individuals, particularly females, during their second to fourth decades of life. The concurrent occurrence of oral squamous cell carcinoma (OSCC) with ossifying fibroma is exceedingly rare, with only one previous case reported. CASE REPORT: We describe a 71-year-old male presenting with a gradually enlarging swelling in the oral cavity, initially treated five years prior for a mandibular fracture. Clinical examination revealed a large swelling in the right maxillary area, and imaging showed a radiolucent lesion with expansile characteristics. Histopathological analysis of the excised tissue initially suggested a benign fibro-osseous lesion. However, upon recurrence, a further biopsy revealed a coexistence of ossifying fibroma and well-differentiated squamous cell carcinoma in the previously affected palatal region. DISCUSSION: The simultaneous presence of ossifying fibroma and OSCC is extremely rare. This case underscores the importance of thorough diagnostic evaluation and highlights potential associations between trauma and tumor development. Further research is needed to elucidate the relationship between these lesions and improve diagnostic and therapeutic approaches for such rare occurrences. https://bjohns.in/journal23/index.php/bjohns/article/view/139Fibro-osseous lesionMaxillary sinusOssifying fibromaOral squamous cell carcinoma |
| spellingShingle | Navya Jacob Murali T V Indu M Amilu Elsa Varghese Ossifying Fibroma with Co-existent Squamous Cell Carcinoma in Maxilla Bengal Journal of Otolaryngology and Head Neck Surgery Fibro-osseous lesion Maxillary sinus Ossifying fibroma Oral squamous cell carcinoma |
| title | Ossifying Fibroma with Co-existent Squamous Cell Carcinoma in Maxilla |
| title_full | Ossifying Fibroma with Co-existent Squamous Cell Carcinoma in Maxilla |
| title_fullStr | Ossifying Fibroma with Co-existent Squamous Cell Carcinoma in Maxilla |
| title_full_unstemmed | Ossifying Fibroma with Co-existent Squamous Cell Carcinoma in Maxilla |
| title_short | Ossifying Fibroma with Co-existent Squamous Cell Carcinoma in Maxilla |
| title_sort | ossifying fibroma with co existent squamous cell carcinoma in maxilla |
| topic | Fibro-osseous lesion Maxillary sinus Ossifying fibroma Oral squamous cell carcinoma |
| url | https://bjohns.in/journal23/index.php/bjohns/article/view/139 |
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