Successful combined endoscopic treatment (photodynamic therapy+electrocautery) of patient with early cancer of lower third esophagus (14 year follow up)

The case of successful use of photodynamic therapy (PDT) combined with electrocautery for treatment of patients with cancer or lower third esophagous is reported. The patient had well-differentiated adenocarcinoma with underlying intestinal metaplasia and I– III displasya. The organ-preserving endos...

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Main Authors: V. V. Sokolov, Е. S. Karpova, Е. V. Filonenko, T. A. Belous, G. A. Frank
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2013-03-01
Series:Biomedical Photonics
Subjects:
Online Access:https://www.pdt-journal.com/jour/article/view/8
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author V. V. Sokolov
Е. S. Karpova
Е. V. Filonenko
T. A. Belous
G. A. Frank
author_facet V. V. Sokolov
Е. S. Karpova
Е. V. Filonenko
T. A. Belous
G. A. Frank
author_sort V. V. Sokolov
collection DOAJ
description The case of successful use of photodynamic therapy (PDT) combined with electrocautery for treatment of patients with cancer or lower third esophagous is reported. The patient had well-differentiated adenocarcinoma with underlying intestinal metaplasia and I– III displasya. The organ-preserving endoscopic treatment was performed: PDT with phogem (2 courses) combined with electrocautery of tumor (3 sessions). Photogem was administered i.v. in dose 3.0 mg/kg 48 h prior to each session of irradiation (635 nm, light dose 150 J/cm2). Three months after treatment additional PDT in described regimen was performed for residual tumor. The followup accounted for 14 years, the complete regression of esophageal tumor with good functional result without scar deformation and stenosis was observed.
format Article
id doaj-art-e5c2b73ca9e546759bd3f81a01266ad2
institution DOAJ
issn 2413-9432
language Russian
publishDate 2013-03-01
publisher Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
record_format Article
series Biomedical Photonics
spelling doaj-art-e5c2b73ca9e546759bd3f81a01266ad22025-08-20T03:00:54ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322013-03-012148518Successful combined endoscopic treatment (photodynamic therapy+electrocautery) of patient with early cancer of lower third esophagus (14 year follow up)V. V. Sokolov0Е. S. Karpova1Е. V. Filonenko2T. A. Belous3G. A. Frank4P.A.Herzen Moscow Cancer Research InstituteP.A.Herzen Moscow Cancer Research InstituteP.A.Herzen Moscow Cancer Research InstituteP.A.Herzen Moscow Cancer Research InstituteP.A.Herzen Moscow Cancer Research InstituteThe case of successful use of photodynamic therapy (PDT) combined with electrocautery for treatment of patients with cancer or lower third esophagous is reported. The patient had well-differentiated adenocarcinoma with underlying intestinal metaplasia and I– III displasya. The organ-preserving endoscopic treatment was performed: PDT with phogem (2 courses) combined with electrocautery of tumor (3 sessions). Photogem was administered i.v. in dose 3.0 mg/kg 48 h prior to each session of irradiation (635 nm, light dose 150 J/cm2). Three months after treatment additional PDT in described regimen was performed for residual tumor. The followup accounted for 14 years, the complete regression of esophageal tumor with good functional result without scar deformation and stenosis was observed.https://www.pdt-journal.com/jour/article/view/8esophageal cancerendoscopic photodynamic therapyelectrocautery
spellingShingle V. V. Sokolov
Е. S. Karpova
Е. V. Filonenko
T. A. Belous
G. A. Frank
Successful combined endoscopic treatment (photodynamic therapy+electrocautery) of patient with early cancer of lower third esophagus (14 year follow up)
Biomedical Photonics
esophageal cancer
endoscopic photodynamic therapy
electrocautery
title Successful combined endoscopic treatment (photodynamic therapy+electrocautery) of patient with early cancer of lower third esophagus (14 year follow up)
title_full Successful combined endoscopic treatment (photodynamic therapy+electrocautery) of patient with early cancer of lower third esophagus (14 year follow up)
title_fullStr Successful combined endoscopic treatment (photodynamic therapy+electrocautery) of patient with early cancer of lower third esophagus (14 year follow up)
title_full_unstemmed Successful combined endoscopic treatment (photodynamic therapy+electrocautery) of patient with early cancer of lower third esophagus (14 year follow up)
title_short Successful combined endoscopic treatment (photodynamic therapy+electrocautery) of patient with early cancer of lower third esophagus (14 year follow up)
title_sort successful combined endoscopic treatment photodynamic therapy electrocautery of patient with early cancer of lower third esophagus 14 year follow up
topic esophageal cancer
endoscopic photodynamic therapy
electrocautery
url https://www.pdt-journal.com/jour/article/view/8
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AT eskarpova successfulcombinedendoscopictreatmentphotodynamictherapyelectrocauteryofpatientwithearlycanceroflowerthirdesophagus14yearfollowup
AT evfilonenko successfulcombinedendoscopictreatmentphotodynamictherapyelectrocauteryofpatientwithearlycanceroflowerthirdesophagus14yearfollowup
AT tabelous successfulcombinedendoscopictreatmentphotodynamictherapyelectrocauteryofpatientwithearlycanceroflowerthirdesophagus14yearfollowup
AT gafrank successfulcombinedendoscopictreatmentphotodynamictherapyelectrocauteryofpatientwithearlycanceroflowerthirdesophagus14yearfollowup