Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer
Abstract Cell‐intrinsic metabolic reprogramming is a hallmark of cancer that provides anabolic support to cell proliferation. How reprogramming influences tumor heterogeneity or drug sensitivities is not well understood. Here, we report a self‐organizing spatial pattern of glycolysis in xenograft co...
Saved in:
| Main Authors: | Mary Lee, George T Chen, Eric Puttock, Kehui Wang, Robert A Edwards, Marian L Waterman, John Lowengrub |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2017-02-01
|
| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.20167386 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Axin2 coupled excessive Wnt‐glycolysis signaling mediates social defect in autism spectrum disorders
by: Mengmeng Wang, et al.
Published: (2023-04-01) -
Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling
by: Joseph Hanna, et al.
Published: (2025-06-01) -
Ciprofol suppresses glycolysis and EMT in colorectal cancer cells by activating APC to modulate the Wnt/β-catenin signaling pathway
by: Han Wu, et al.
Published: (2025-07-01) -
Free Methylglyoxal and Lactate Produced and Released by Cultured Cancer and Non-Cancer Cells: Implications for Tumor Growth and Development
by: Dominique Belpomme, et al.
Published: (2025-06-01) -
Warburg-like Metabolic Reprogramming in Endometriosis: From Molecular Mechanisms to Therapeutic Approaches
by: Bo-Sung Kim, et al.
Published: (2025-05-01)