Spontaneous Coronary Artery Dissection
Despite marked advancements in the recognition and diagnosis of spontaneous coronary artery dissection (SCAD) over the past decade, knowledge of the basic pathophysiologic mechanisms of disease, contributing factors, and treatment continue to be poorly understood. We describe significant research ga...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | JACC: Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772963X24006653 |
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| author | Daniela Crousillat, MD Amy Sarma, MD Malissa Wood, MD Sahar Naderi, MD, MHS Katherine Leon, MS C Michael Gibson, MD Aaron Aday, MD, MSc Anna Grodzinsky, MD, MS Kathy Izard, BA Jason C. Kovacic, MD, PhD Mark E. Lindsay, MD, PhD Dermot Phelan, MD, PhD Patricia F. Rodriguez-Lozano, MD, MS Nandita S. Scott, MD Markus Scherer, MD Aditya Sharma, MD Ranya Sweis, MD Jennifer A. Sumner, PhD Esther S.H. Kim, MD, MPH |
| author_facet | Daniela Crousillat, MD Amy Sarma, MD Malissa Wood, MD Sahar Naderi, MD, MHS Katherine Leon, MS C Michael Gibson, MD Aaron Aday, MD, MSc Anna Grodzinsky, MD, MS Kathy Izard, BA Jason C. Kovacic, MD, PhD Mark E. Lindsay, MD, PhD Dermot Phelan, MD, PhD Patricia F. Rodriguez-Lozano, MD, MS Nandita S. Scott, MD Markus Scherer, MD Aditya Sharma, MD Ranya Sweis, MD Jennifer A. Sumner, PhD Esther S.H. Kim, MD, MPH |
| author_sort | Daniela Crousillat, MD |
| collection | DOAJ |
| description | Despite marked advancements in the recognition and diagnosis of spontaneous coronary artery dissection (SCAD) over the past decade, knowledge of the basic pathophysiologic mechanisms of disease, contributing factors, and treatment continue to be poorly understood. We describe significant research gaps in our knowledge of SCAD and introduce strategies including the role of patient advocacy, independent registries, and creation of diverse centers of excellence to bridge the gap in clinical care, research, and outcomes. Lastly, we introduce an innovative patient-centered clinical care and research framework established through the SCAD Alliance and International Spontaneous Coronary Artery Dissection registry as a model for advancing knowledge of SCAD. |
| format | Article |
| id | doaj-art-e5b16131a7aa4823b76309b72c25dcff |
| institution | OA Journals |
| issn | 2772-963X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JACC: Advances |
| spelling | doaj-art-e5b16131a7aa4823b76309b72c25dcff2025-08-20T02:32:44ZengElsevierJACC: Advances2772-963X2024-12-0131210138510.1016/j.jacadv.2024.101385Spontaneous Coronary Artery DissectionDaniela Crousillat, MD0Amy Sarma, MD1Malissa Wood, MD2Sahar Naderi, MD, MHS3Katherine Leon, MS4C Michael Gibson, MD5Aaron Aday, MD, MSc6Anna Grodzinsky, MD, MS7Kathy Izard, BA8Jason C. Kovacic, MD, PhD9Mark E. Lindsay, MD, PhD10Dermot Phelan, MD, PhD11Patricia F. Rodriguez-Lozano, MD, MS12Nandita S. Scott, MD13Markus Scherer, MD14Aditya Sharma, MD15Ranya Sweis, MD16Jennifer A. Sumner, PhD17Esther S.H. Kim, MD, MPH18Division of Cardiovascular Sciences, Department of Medicine and Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, Tampa General Hospital Heart and Vascular Institute, Tampa, Florida, USADivision of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USADivision- Heart Institute, Lee Health Heart Institute, Fort Myers, Florida, USADivision of Cardiology, Kaiser Permanente Northern California, San Francisco, California, USASCAD Alliance, Alexandria, Virginia, USAPERFUSE Study Group, Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USAVanderbilt Translational and Clinical Cardiovascular Research Center, Nashville, Tennessee, USASaint Luke’s Mid America Heart Institute/University of Missouri-Kansas City, Kansas City, Missouri, USASCAD Alliance, Alexandria, Virginia, USACardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Vascular Biology Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia; St. Vincent's Clinical School, University of NSW, Sydney, New South Wales, AustraliaCardiovascular Genetics Program, Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USAGragg Center for Cardiovascular Performance, Sanger Heart & Vascular Institute, Atrium Health, Charlotte, North Carolina, USACardiovascular Division, Department of Medicine, University of Virginia Health, Charlottesville, Virginia, USADivision of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USASanger Heart and Vascular Institute, Atrium Health, Charlotte, North Carolina, USADivision of Cardiovascular Medicine, University of Virginia, Charlottesville, Virginia, USADivision of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USADepartment of Psychology, University of California, Los Angeles, California, USASanger Heart & Vascular Institute, Atrium Health, Charlotte, North Carolina, USA; Address for correspondence: Dr Esther S.H. Kim, Atrium Health, 1237 Harding Place, Suite 2300, Charlotte, North Carolina 28204, USA.Despite marked advancements in the recognition and diagnosis of spontaneous coronary artery dissection (SCAD) over the past decade, knowledge of the basic pathophysiologic mechanisms of disease, contributing factors, and treatment continue to be poorly understood. We describe significant research gaps in our knowledge of SCAD and introduce strategies including the role of patient advocacy, independent registries, and creation of diverse centers of excellence to bridge the gap in clinical care, research, and outcomes. Lastly, we introduce an innovative patient-centered clinical care and research framework established through the SCAD Alliance and International Spontaneous Coronary Artery Dissection registry as a model for advancing knowledge of SCAD.http://www.sciencedirect.com/science/article/pii/S2772963X24006653SCADhealth inequitysex differences |
| spellingShingle | Daniela Crousillat, MD Amy Sarma, MD Malissa Wood, MD Sahar Naderi, MD, MHS Katherine Leon, MS C Michael Gibson, MD Aaron Aday, MD, MSc Anna Grodzinsky, MD, MS Kathy Izard, BA Jason C. Kovacic, MD, PhD Mark E. Lindsay, MD, PhD Dermot Phelan, MD, PhD Patricia F. Rodriguez-Lozano, MD, MS Nandita S. Scott, MD Markus Scherer, MD Aditya Sharma, MD Ranya Sweis, MD Jennifer A. Sumner, PhD Esther S.H. Kim, MD, MPH Spontaneous Coronary Artery Dissection JACC: Advances SCAD health inequity sex differences |
| title | Spontaneous Coronary Artery Dissection |
| title_full | Spontaneous Coronary Artery Dissection |
| title_fullStr | Spontaneous Coronary Artery Dissection |
| title_full_unstemmed | Spontaneous Coronary Artery Dissection |
| title_short | Spontaneous Coronary Artery Dissection |
| title_sort | spontaneous coronary artery dissection |
| topic | SCAD health inequity sex differences |
| url | http://www.sciencedirect.com/science/article/pii/S2772963X24006653 |
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