Glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosis

Aim. To investigate the relationship between abnormal glycemia levels during inpatient treatment for acute myocardial infarction (AMI) in patients with type 2 diabetes (T2D) and long-term prognosis.Material and methods. The single-center cohort study included patients with AMI and concomitant T2D wh...

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Main Authors: M. A. Korotina, I. G. Pochinka, A. A. Frolov, S. N. Botova, L. G. Strongin
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2021-04-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/4239
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author M. A. Korotina
I. G. Pochinka
A. A. Frolov
S. N. Botova
L. G. Strongin
author_facet M. A. Korotina
I. G. Pochinka
A. A. Frolov
S. N. Botova
L. G. Strongin
author_sort M. A. Korotina
collection DOAJ
description Aim. To investigate the relationship between abnormal glycemia levels during inpatient treatment for acute myocardial infarction (AMI) in patients with type 2 diabetes (T2D) and long-term prognosis.Material and methods. The single-center cohort study included patients with AMI and concomitant T2D who were hospitalized consecutively for 200 days. A total of 237 patients were included. The median number of blood glucose measurements during hospitalization was 15 [8; 20] times. Long-term outcome was estimated at 365 days after hospitalization.Results. The first glycemic value on admission was 13,6±5,9, while the average glycemia during hospitalization was 10,0±3,5 mmol/L. Within 12 follow-up period, 53 deaths were recorded. It was found that exceeding the glycemic threshold of 10,0 mmol/L in more than 45% of measurements during hospitalization was associated with a 3-fold increase in the risk of an unfavorable outcome within 12 months. Predictors of poor glycemic control are insulin therapy before MI and blood glucose at admission >12,1 mmol/L.Conclusion. Poor glycemic control (>45% of glucose measurements above the threshold of 10,0 mmol/L) during hospitalization for AMI in patients with T2D is associated with an increased risk of in-hospital death and during the next 12 months, including in patients who underwent endovascular treatment.
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spelling doaj-art-e5b09d59b3004d0db73c261ac6f81d112025-08-20T03:21:31Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202021-04-0126310.15829/1560-4071-2021-42393153Glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosisM. A. Korotina0I. G. Pochinka1A. A. Frolov2S. N. Botova3L. G. Strongin4Privolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityAim. To investigate the relationship between abnormal glycemia levels during inpatient treatment for acute myocardial infarction (AMI) in patients with type 2 diabetes (T2D) and long-term prognosis.Material and methods. The single-center cohort study included patients with AMI and concomitant T2D who were hospitalized consecutively for 200 days. A total of 237 patients were included. The median number of blood glucose measurements during hospitalization was 15 [8; 20] times. Long-term outcome was estimated at 365 days after hospitalization.Results. The first glycemic value on admission was 13,6±5,9, while the average glycemia during hospitalization was 10,0±3,5 mmol/L. Within 12 follow-up period, 53 deaths were recorded. It was found that exceeding the glycemic threshold of 10,0 mmol/L in more than 45% of measurements during hospitalization was associated with a 3-fold increase in the risk of an unfavorable outcome within 12 months. Predictors of poor glycemic control are insulin therapy before MI and blood glucose at admission >12,1 mmol/L.Conclusion. Poor glycemic control (>45% of glucose measurements above the threshold of 10,0 mmol/L) during hospitalization for AMI in patients with T2D is associated with an increased risk of in-hospital death and during the next 12 months, including in patients who underwent endovascular treatment.https://russjcardiol.elpub.ru/jour/article/view/4239myocardial infarctiondiabetesglycemic control
spellingShingle M. A. Korotina
I. G. Pochinka
A. A. Frolov
S. N. Botova
L. G. Strongin
Glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosis
Российский кардиологический журнал
myocardial infarction
diabetes
glycemic control
title Glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosis
title_full Glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosis
title_fullStr Glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosis
title_full_unstemmed Glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosis
title_short Glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction: impact on prognosis
title_sort glycemia in patients with type 2 diabetes during inpatient treatment for acute myocardial infarction impact on prognosis
topic myocardial infarction
diabetes
glycemic control
url https://russjcardiol.elpub.ru/jour/article/view/4239
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AT igpochinka glycemiainpatientswithtype2diabetesduringinpatienttreatmentforacutemyocardialinfarctionimpactonprognosis
AT aafrolov glycemiainpatientswithtype2diabetesduringinpatienttreatmentforacutemyocardialinfarctionimpactonprognosis
AT snbotova glycemiainpatientswithtype2diabetesduringinpatienttreatmentforacutemyocardialinfarctionimpactonprognosis
AT lgstrongin glycemiainpatientswithtype2diabetesduringinpatienttreatmentforacutemyocardialinfarctionimpactonprognosis