Concomitant Infection of Helicobacter pylori and Intestinal Parasites: Burden, Sociodemographic and Clinical Characteristics in Hospitalized Children and Adolescents in Northern Lebanon [version 2; peer review: 1 approved, 2 approved with reservations]
Background Helicobacter pylori and intestinal parasites are well-known for their high prevalence in children, especially in developing countries. However, their concomitant infections are poorly documented. In this study, we aimed to evaluate the association between intestinal parasites and H. pylor...
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F1000 Research Ltd
2024-10-01
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| author | Ghalia Khoder Nour Mina Sara Daher Sara MINA |
| author_facet | Ghalia Khoder Nour Mina Sara Daher Sara MINA |
| author_sort | Ghalia Khoder |
| collection | DOAJ |
| description | Background Helicobacter pylori and intestinal parasites are well-known for their high prevalence in children, especially in developing countries. However, their concomitant infections are poorly documented. In this study, we aimed to evaluate the association between intestinal parasites and H. pylori among hospitalized children and adolescents with upper gastrointestinal complaints in Northern Lebanon. Methods A cross-sectional study was conducted involving 297 hospitalized pediatric patients, aged between 1 and 15 years, who presented with gastrointestinal symptoms. The socio-demographic, lifestyle, and gastrointestinal characteristics of all participants were analyzed. Fresh stool samples were collected and screened for the presence of intestinal parasites and H. pylori infections. Results 6.4% of the patients were positive for intestinal parasitic infections, 5.4% were positive for H. pylori infection, and 11.8% were co-infected. The results of the Chi-square test showed that H. pylori infection is significantly associated with parasitic infection but not with a particular species. The most frequent coinfection was H. pylori-Entamoeba histolytica (77.1%). Moreover, H. pylori infection was associated with overcrowding and infrequent washing of vegetables before eating. The prevalence of co-infections increased in patients of mothers with a primary educational level or less. In regards to clinical characteristics, our findings showed a statistically significant relationship between i) gastric reflux and H. pylori, and ii) severe diarrhea and parasitic infection. Conclusion Our data highlighted the association between H. pylori and intestinal parasitic infections. Thus, H. pylori detection could be taken into consideration while screening for parasitic infections in children and adolescents. |
| format | Article |
| id | doaj-art-e5af6f1b579b4d929f0604ca01bc6637 |
| institution | OA Journals |
| issn | 2046-1402 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | F1000 Research Ltd |
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| spelling | doaj-art-e5af6f1b579b4d929f0604ca01bc66372025-08-20T01:57:48ZengF1000 Research LtdF1000Research2046-14022024-10-011310.12688/f1000research.148550.2172946Concomitant Infection of Helicobacter pylori and Intestinal Parasites: Burden, Sociodemographic and Clinical Characteristics in Hospitalized Children and Adolescents in Northern Lebanon [version 2; peer review: 1 approved, 2 approved with reservations]Ghalia Khoder0Nour Mina1https://orcid.org/0000-0002-2477-4583Sara Daher2Sara MINA3Sharjah Institute for Medical Research, University of Sharjah, Sharjah, Sharjah, 27272, United Arab EmiratesFaculty of Medicine, Beirut Arab University, Beirut, 11-5020, LebanonFaculty of Public Health 3, L.S.E.E, Lebanese University, Tripoli, LebanonDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, Beirut Arab University, Beirut, 11-5020, LebanonBackground Helicobacter pylori and intestinal parasites are well-known for their high prevalence in children, especially in developing countries. However, their concomitant infections are poorly documented. In this study, we aimed to evaluate the association between intestinal parasites and H. pylori among hospitalized children and adolescents with upper gastrointestinal complaints in Northern Lebanon. Methods A cross-sectional study was conducted involving 297 hospitalized pediatric patients, aged between 1 and 15 years, who presented with gastrointestinal symptoms. The socio-demographic, lifestyle, and gastrointestinal characteristics of all participants were analyzed. Fresh stool samples were collected and screened for the presence of intestinal parasites and H. pylori infections. Results 6.4% of the patients were positive for intestinal parasitic infections, 5.4% were positive for H. pylori infection, and 11.8% were co-infected. The results of the Chi-square test showed that H. pylori infection is significantly associated with parasitic infection but not with a particular species. The most frequent coinfection was H. pylori-Entamoeba histolytica (77.1%). Moreover, H. pylori infection was associated with overcrowding and infrequent washing of vegetables before eating. The prevalence of co-infections increased in patients of mothers with a primary educational level or less. In regards to clinical characteristics, our findings showed a statistically significant relationship between i) gastric reflux and H. pylori, and ii) severe diarrhea and parasitic infection. Conclusion Our data highlighted the association between H. pylori and intestinal parasitic infections. Thus, H. pylori detection could be taken into consideration while screening for parasitic infections in children and adolescents.https://f1000research.com/articles/13-500/v2Co-infection Lebanon Intestinal parasites Helicobacter pylori Stool.eng |
| spellingShingle | Ghalia Khoder Nour Mina Sara Daher Sara MINA Concomitant Infection of Helicobacter pylori and Intestinal Parasites: Burden, Sociodemographic and Clinical Characteristics in Hospitalized Children and Adolescents in Northern Lebanon [version 2; peer review: 1 approved, 2 approved with reservations] F1000Research Co-infection Lebanon Intestinal parasites Helicobacter pylori Stool. eng |
| title | Concomitant Infection of Helicobacter pylori and Intestinal Parasites: Burden, Sociodemographic and Clinical Characteristics in Hospitalized Children and Adolescents in Northern Lebanon [version 2; peer review: 1 approved, 2 approved with reservations] |
| title_full | Concomitant Infection of Helicobacter pylori and Intestinal Parasites: Burden, Sociodemographic and Clinical Characteristics in Hospitalized Children and Adolescents in Northern Lebanon [version 2; peer review: 1 approved, 2 approved with reservations] |
| title_fullStr | Concomitant Infection of Helicobacter pylori and Intestinal Parasites: Burden, Sociodemographic and Clinical Characteristics in Hospitalized Children and Adolescents in Northern Lebanon [version 2; peer review: 1 approved, 2 approved with reservations] |
| title_full_unstemmed | Concomitant Infection of Helicobacter pylori and Intestinal Parasites: Burden, Sociodemographic and Clinical Characteristics in Hospitalized Children and Adolescents in Northern Lebanon [version 2; peer review: 1 approved, 2 approved with reservations] |
| title_short | Concomitant Infection of Helicobacter pylori and Intestinal Parasites: Burden, Sociodemographic and Clinical Characteristics in Hospitalized Children and Adolescents in Northern Lebanon [version 2; peer review: 1 approved, 2 approved with reservations] |
| title_sort | concomitant infection of helicobacter pylori and intestinal parasites burden sociodemographic and clinical characteristics in hospitalized children and adolescents in northern lebanon version 2 peer review 1 approved 2 approved with reservations |
| topic | Co-infection Lebanon Intestinal parasites Helicobacter pylori Stool. eng |
| url | https://f1000research.com/articles/13-500/v2 |
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