A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics
Expression of many bacterial genes is regulated by cis- and trans-acting elements in their 5’ upstream regions (URs). Cis-acting regulatory elements in URs include upstream ORFs (uORFs), short ORFs that sense translation stress that manifests as ribosomes stalling at specific codons within the uORF....
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2025-05-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/101217 |
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