Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i>
<i>Adenocaulon himalaicum</i> is widely distributed across Asia. In its early growth stages, <i>A. himalaicum</i> is traditionally consumed as a food source in Korea. Although previous research has identified the presence of bioactive compounds in <i>A. himalaicum</i...
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2025-03-01
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| author | Sang-Yun Lee Nari Yoon Neil Patrick Uy Chung-Ho Choi Sanghyun Lee |
| author_facet | Sang-Yun Lee Nari Yoon Neil Patrick Uy Chung-Ho Choi Sanghyun Lee |
| author_sort | Sang-Yun Lee |
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| description | <i>Adenocaulon himalaicum</i> is widely distributed across Asia. In its early growth stages, <i>A. himalaicum</i> is traditionally consumed as a food source in Korea. Although previous research has identified the presence of bioactive compounds in <i>A. himalaicum</i> extract, suggesting its potential as a medicinal resource, the phytochemical profile of <i>A. himalaicum</i> extract has not been extensively determined. This investigation aimed to identify the phytochemicals present in the true leaf and cotyledon of <i>A. himalaicum</i> (TLA and CLA, respectively) and evaluate their radical-scavenging activity. By performing LC-MS/MS and HPLC, varying amounts of isochlorogenic acid A, cryptochlorogenic acid, isochlorogenic acid B, rutin, chlorogenic acid, hyperin, and neochlorogenic acid were detected in the TLA and CLA extracts. Chlorogenic acid (9.002 mg/g DW), isochlorogenic acid A (28.512 mg/g DW), and isochlorogenic acid B (12.223 mg/g DW) were the most abundant in TLA. TLA exhibited higher phytochemical content (49.737 mg/g DW), total phenolic content (45.51 mg tannic acid equivalent/g extract), and total flavonoid content (16.24 mg quercetin equivalent/g extract) than CLA. Moreover, the radical-scavenging activity of TLA was two times higher than that of CLA. The young leaf of <i>A. himalaicum</i> has a rich phytochemical profile and robust antioxidant activity; hence, it has potential as natural antioxidant sources for human health and valuable pharmacognosy raw materials for pharmaceutical and functional food applications. |
| format | Article |
| id | doaj-art-e5af1c38600945cdbc427c8e31a332c8 |
| institution | DOAJ |
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| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
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| series | ChemEngineering |
| spelling | doaj-art-e5af1c38600945cdbc427c8e31a332c82025-08-20T03:14:17ZengMDPI AGChemEngineering2305-70842025-03-01923110.3390/chemengineering9020031Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i>Sang-Yun Lee0Nari Yoon1Neil Patrick Uy2Chung-Ho Choi3Sanghyun Lee4Department of Plant Science and Technology, Chung-Ang University, Anseong 17546, Republic of KoreaDepartment of Plant Science and Technology, Chung-Ang University, Anseong 17546, Republic of KoreaDepartment of Plant Science and Technology, Chung-Ang University, Anseong 17546, Republic of KoreaGyeonggi-do Forestry Environment Research Center, Osan 18118, Republic of KoreaDepartment of Plant Science and Technology, Chung-Ang University, Anseong 17546, Republic of Korea<i>Adenocaulon himalaicum</i> is widely distributed across Asia. In its early growth stages, <i>A. himalaicum</i> is traditionally consumed as a food source in Korea. Although previous research has identified the presence of bioactive compounds in <i>A. himalaicum</i> extract, suggesting its potential as a medicinal resource, the phytochemical profile of <i>A. himalaicum</i> extract has not been extensively determined. This investigation aimed to identify the phytochemicals present in the true leaf and cotyledon of <i>A. himalaicum</i> (TLA and CLA, respectively) and evaluate their radical-scavenging activity. By performing LC-MS/MS and HPLC, varying amounts of isochlorogenic acid A, cryptochlorogenic acid, isochlorogenic acid B, rutin, chlorogenic acid, hyperin, and neochlorogenic acid were detected in the TLA and CLA extracts. Chlorogenic acid (9.002 mg/g DW), isochlorogenic acid A (28.512 mg/g DW), and isochlorogenic acid B (12.223 mg/g DW) were the most abundant in TLA. TLA exhibited higher phytochemical content (49.737 mg/g DW), total phenolic content (45.51 mg tannic acid equivalent/g extract), and total flavonoid content (16.24 mg quercetin equivalent/g extract) than CLA. Moreover, the radical-scavenging activity of TLA was two times higher than that of CLA. The young leaf of <i>A. himalaicum</i> has a rich phytochemical profile and robust antioxidant activity; hence, it has potential as natural antioxidant sources for human health and valuable pharmacognosy raw materials for pharmaceutical and functional food applications.https://www.mdpi.com/2305-7084/9/2/31<i>Adenocaulon himalaicum</i>antioxidantsLC-MS/MSHPLC |
| spellingShingle | Sang-Yun Lee Nari Yoon Neil Patrick Uy Chung-Ho Choi Sanghyun Lee Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i> ChemEngineering <i>Adenocaulon himalaicum</i> antioxidants LC-MS/MS HPLC |
| title | Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i> |
| title_full | Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i> |
| title_fullStr | Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i> |
| title_full_unstemmed | Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i> |
| title_short | Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i> |
| title_sort | phytochemical profiling and antioxidant activity of true leaves and cotyledons of i adenocaulon himalaicum i |
| topic | <i>Adenocaulon himalaicum</i> antioxidants LC-MS/MS HPLC |
| url | https://www.mdpi.com/2305-7084/9/2/31 |
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