Testosterone Replacement Therapy and the Risk of Hypoglycemia

We report the case of a 45-year-old man with a history of Klinefelter syndrome undergoing testosterone replacement therapy, and with type 2 diabetes treated with metformin with poor metabolic control. When vildagliptin was added to his treatment, he presented hypoglycemia after the testosterone inje...

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Main Authors: Analía Verónica Yamaguchi, Pablo René Costanzo, Verónica Andrea Peuchot, Pablo Knoblovits
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2019/9616125
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author Analía Verónica Yamaguchi
Pablo René Costanzo
Verónica Andrea Peuchot
Pablo Knoblovits
author_facet Analía Verónica Yamaguchi
Pablo René Costanzo
Verónica Andrea Peuchot
Pablo Knoblovits
author_sort Analía Verónica Yamaguchi
collection DOAJ
description We report the case of a 45-year-old man with a history of Klinefelter syndrome undergoing testosterone replacement therapy, and with type 2 diabetes treated with metformin with poor metabolic control. When vildagliptin was added to his treatment, he presented hypoglycemia after the testosterone injection. We highlight this not widely reported drug interaction between hypoglycemic agents and testosterone.
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institution Kabale University
issn 2090-6501
2090-651X
language English
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series Case Reports in Endocrinology
spelling doaj-art-e5a8ae29e0dd41c8bf6ca26af0dcc4582025-08-20T03:26:17ZengWileyCase Reports in Endocrinology2090-65012090-651X2019-01-01201910.1155/2019/96161259616125Testosterone Replacement Therapy and the Risk of HypoglycemiaAnalía Verónica Yamaguchi0Pablo René Costanzo1Verónica Andrea Peuchot2Pablo Knoblovits3Clinical Medicine Department, Metabolism and Nuclear Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaDepartment of Endocrinology, Metabolism and Nuclear Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaClinical Medicine Department, Metabolism and Nuclear Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaDepartment of Endocrinology, Metabolism and Nuclear Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaWe report the case of a 45-year-old man with a history of Klinefelter syndrome undergoing testosterone replacement therapy, and with type 2 diabetes treated with metformin with poor metabolic control. When vildagliptin was added to his treatment, he presented hypoglycemia after the testosterone injection. We highlight this not widely reported drug interaction between hypoglycemic agents and testosterone.http://dx.doi.org/10.1155/2019/9616125
spellingShingle Analía Verónica Yamaguchi
Pablo René Costanzo
Verónica Andrea Peuchot
Pablo Knoblovits
Testosterone Replacement Therapy and the Risk of Hypoglycemia
Case Reports in Endocrinology
title Testosterone Replacement Therapy and the Risk of Hypoglycemia
title_full Testosterone Replacement Therapy and the Risk of Hypoglycemia
title_fullStr Testosterone Replacement Therapy and the Risk of Hypoglycemia
title_full_unstemmed Testosterone Replacement Therapy and the Risk of Hypoglycemia
title_short Testosterone Replacement Therapy and the Risk of Hypoglycemia
title_sort testosterone replacement therapy and the risk of hypoglycemia
url http://dx.doi.org/10.1155/2019/9616125
work_keys_str_mv AT analiaveronicayamaguchi testosteronereplacementtherapyandtheriskofhypoglycemia
AT pablorenecostanzo testosteronereplacementtherapyandtheriskofhypoglycemia
AT veronicaandreapeuchot testosteronereplacementtherapyandtheriskofhypoglycemia
AT pabloknoblovits testosteronereplacementtherapyandtheriskofhypoglycemia