Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells

Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells

Two new synthesized and characterized quinazoline Schiff bases 1 and 2 were investigated for anticancer activity against MCF-7 human breast cancer cell line. Compounds 1 and 2 demonstrated a remarkable antiproliferative effect, with an IC50 value of 6.246 × 10−6 mol/L and 5.910 × 10−6 mol/L, respec...

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Bibliographic Details
Main Authors:	Fadhil Lafta Faraj, Maryam Zahedifard, Mohammadjavad Paydar, Chung Yeng Looi, Nazia Abdul Majid, Hapipah Mohd Ali, Noraini Ahmad, Nura Suleiman Gwaram, Mahmood Ameen Abdulla
Format:	Article
Language:	English
Published:	Wiley 2014-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1155/2014/212096
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