Minocycline-Associated Pseudotumor Cerebri with Severe Papilledema

Background. Pseudotumor cerebri is an acknowledged but unusual complication of oral minocycline use. Vision loss and papilledema have been described as mild and transient, and some authors suggest that treatment is not needed. Methods. Case series of 2 patients with severe papilledema and visual fie...

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Main Authors: Simon R. Bababeygy, Michael X. Repka, Prem S. Subramanian
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2009/203583
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author Simon R. Bababeygy
Michael X. Repka
Prem S. Subramanian
author_facet Simon R. Bababeygy
Michael X. Repka
Prem S. Subramanian
author_sort Simon R. Bababeygy
collection DOAJ
description Background. Pseudotumor cerebri is an acknowledged but unusual complication of oral minocycline use. Vision loss and papilledema have been described as mild and transient, and some authors suggest that treatment is not needed. Methods. Case series of 2 patients with severe papilledema and visual field loss. Results. Severe pseudotumor cerebri developed in 2 nonobese patients taking minocycline. Their disease required further treatment even upon drug discontinuation because of visual field loss and papilledema. Conclusions. Minocycline-associated pseudotumor cerebri is not always a self-limited condition and may require aggressive medical or surgical management.
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spelling doaj-art-e59f9abb07534b09aa41d594b8790f932025-08-20T02:21:19ZengWileyJournal of Ophthalmology2090-004X2090-00582009-01-01200910.1155/2009/203583203583Minocycline-Associated Pseudotumor Cerebri with Severe PapilledemaSimon R. Bababeygy0Michael X. Repka1Prem S. Subramanian2Department of Ophthalmology, The Johns Hopkins Hospitals, 600 N. Wolfe St, Baltimore, MD 21287, USADepartment of Ophthalmology, The Johns Hopkins Hospitals, 600 N. Wolfe St, Baltimore, MD 21287, USADepartment of Ophthalmology, The Johns Hopkins Hospitals, 600 N. Wolfe St, Baltimore, MD 21287, USABackground. Pseudotumor cerebri is an acknowledged but unusual complication of oral minocycline use. Vision loss and papilledema have been described as mild and transient, and some authors suggest that treatment is not needed. Methods. Case series of 2 patients with severe papilledema and visual field loss. Results. Severe pseudotumor cerebri developed in 2 nonobese patients taking minocycline. Their disease required further treatment even upon drug discontinuation because of visual field loss and papilledema. Conclusions. Minocycline-associated pseudotumor cerebri is not always a self-limited condition and may require aggressive medical or surgical management.http://dx.doi.org/10.1155/2009/203583
spellingShingle Simon R. Bababeygy
Michael X. Repka
Prem S. Subramanian
Minocycline-Associated Pseudotumor Cerebri with Severe Papilledema
Journal of Ophthalmology
title Minocycline-Associated Pseudotumor Cerebri with Severe Papilledema
title_full Minocycline-Associated Pseudotumor Cerebri with Severe Papilledema
title_fullStr Minocycline-Associated Pseudotumor Cerebri with Severe Papilledema
title_full_unstemmed Minocycline-Associated Pseudotumor Cerebri with Severe Papilledema
title_short Minocycline-Associated Pseudotumor Cerebri with Severe Papilledema
title_sort minocycline associated pseudotumor cerebri with severe papilledema
url http://dx.doi.org/10.1155/2009/203583
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AT michaelxrepka minocyclineassociatedpseudotumorcerebriwithseverepapilledema
AT premssubramanian minocyclineassociatedpseudotumorcerebriwithseverepapilledema