Drosophila Toxicogenomics: genetic variation and sexual dimorphism in susceptibility to 4-Methylimidazole

Abstract Background 4-methylimidazole is a ubiquitous and potentially carcinogenic environmental toxicant. Genetic factors that contribute to variation in susceptibility to its toxic effects are challenging to assess in human populations. We used the Drosophila melanogaster Genetic Reference Panel (...

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Bibliographic Details
Main Authors:	Katelynne M. Collins, Elisabeth Howansky, Sarah C. Macon-Foley, Maria E. Adonay, Vijay Shankar, Richard F. Lyman, Nestor Octavio Nazario-Yepiz, Jordyn K. Brooks, Rachel A. Lyman, Trudy F. C. Mackay, Robert R. H. Anholt
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Series:	Human Genomics
Subjects:	Quantitative genetics genome wide association analyses Drosophila Genetic Reference Panel sex-specific effects sexually antagonistic effects network associations with complex traits
Online Access:	https://doi.org/10.1186/s40246-024-00689-3
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Drosophila Toxicogenomics: genetic variation and sexual dimorphism in susceptibility to 4-Methylimidazole

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