Direct immunofluorescence in bullous disorders: A mini-review
Background: Immunofluorescence microscopy is an invaluable tool for different lesions in dermatopathology. These lesions include bullous lesions, vasculitis, and connective tissue disorders/systemic lupus erythematosus. In this review, we take a look at bullous disorders. Some of these diagnos...
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| Format: | Article |
| Language: | English |
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Association of Clinical Pathologists of Nepal
2024-10-01
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| Series: | Journal of Pathology of Nepal |
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| Online Access: | https://www.nepjol.info/index.php/JPN/article/view/67851 |
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| author | Anil Dev Pant |
| author_facet | Anil Dev Pant |
| author_sort | Anil Dev Pant |
| collection | DOAJ |
| description | Background: Immunofluorescence microscopy is an invaluable tool for different lesions in dermatopathology. These lesions include bullous lesions, vasculitis, and connective tissue disorders/systemic lupus erythematosus. In this review, we take a look at bullous disorders.
Some of these diagnoses are not possible on routine histopathology alone and require immunofluorescence for confirmation. Different diseases can be diagnosed according to the immunoglobulins/complements, sites of deposition (dermo-epidermal / intercellular spaces / dermal), and their patterns (linear, granular). Knowing the exact type of lesion can help guide treatment accordingly. |
| format | Article |
| id | doaj-art-e59184d8bd2f4dd3902c08261a864124 |
| institution | Kabale University |
| issn | 2091-0797 2091-0908 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Association of Clinical Pathologists of Nepal |
| record_format | Article |
| series | Journal of Pathology of Nepal |
| spelling | doaj-art-e59184d8bd2f4dd3902c08261a8641242025-08-21T06:55:17ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082024-10-011412167217010.3126/jpn.v14i1.6785194985Direct immunofluorescence in bullous disorders: A mini-reviewAnil Dev Pant0https://orcid.org/0000-0002-2136-5717T. U. Teaching Hospital, Maharajgunj, Kathmandu, Nepal Background: Immunofluorescence microscopy is an invaluable tool for different lesions in dermatopathology. These lesions include bullous lesions, vasculitis, and connective tissue disorders/systemic lupus erythematosus. In this review, we take a look at bullous disorders. Some of these diagnoses are not possible on routine histopathology alone and require immunofluorescence for confirmation. Different diseases can be diagnosed according to the immunoglobulins/complements, sites of deposition (dermo-epidermal / intercellular spaces / dermal), and their patterns (linear, granular). Knowing the exact type of lesion can help guide treatment accordingly.https://www.nepjol.info/index.php/JPN/article/view/67851blistering; bullous; fitc; immunofluorescence; immunoglobulins |
| spellingShingle | Anil Dev Pant Direct immunofluorescence in bullous disorders: A mini-review Journal of Pathology of Nepal blistering; bullous; fitc; immunofluorescence; immunoglobulins |
| title | Direct immunofluorescence in bullous disorders: A mini-review |
| title_full | Direct immunofluorescence in bullous disorders: A mini-review |
| title_fullStr | Direct immunofluorescence in bullous disorders: A mini-review |
| title_full_unstemmed | Direct immunofluorescence in bullous disorders: A mini-review |
| title_short | Direct immunofluorescence in bullous disorders: A mini-review |
| title_sort | direct immunofluorescence in bullous disorders a mini review |
| topic | blistering; bullous; fitc; immunofluorescence; immunoglobulins |
| url | https://www.nepjol.info/index.php/JPN/article/view/67851 |
| work_keys_str_mv | AT anildevpant directimmunofluorescenceinbullousdisordersaminireview |