Direct immunofluorescence in bullous disorders: A mini-review
Background: Immunofluorescence microscopy is an invaluable tool for different lesions in dermatopathology. These lesions include bullous lesions, vasculitis, and connective tissue disorders/systemic lupus erythematosus. In this review, we take a look at bullous disorders. Some of these diagnos...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Association of Clinical Pathologists of Nepal
2024-10-01
|
| Series: | Journal of Pathology of Nepal |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/JPN/article/view/67851 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Background: Immunofluorescence microscopy is an invaluable tool for different lesions in dermatopathology. These lesions include bullous lesions, vasculitis, and connective tissue disorders/systemic lupus erythematosus. In this review, we take a look at bullous disorders.
Some of these diagnoses are not possible on routine histopathology alone and require immunofluorescence for confirmation. Different diseases can be diagnosed according to the immunoglobulins/complements, sites of deposition (dermo-epidermal / intercellular spaces / dermal), and their patterns (linear, granular). Knowing the exact type of lesion can help guide treatment accordingly. |
|---|---|
| ISSN: | 2091-0797 2091-0908 |