PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY
Hence anxiety disorders are frequently observed in the clinical picture of epilepsy these must be considered when choosing adequate therapy. Purpose of this study was evaluation therapeutic efficacy and adverse effects in people with epilepsy treated with pregabalin (PGB) 300 mg per day (20 patients...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2016-08-01
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| Series: | Эпилепсия и пароксизмальные состояния |
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| Online Access: | https://www.epilepsia.su/jour/article/view/187 |
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| author | M. Ya. Kissin I. I. Bondarenko |
| author_facet | M. Ya. Kissin I. I. Bondarenko |
| author_sort | M. Ya. Kissin |
| collection | DOAJ |
| description | Hence anxiety disorders are frequently observed in the clinical picture of epilepsy these must be considered when choosing adequate therapy. Purpose of this study was evaluation therapeutic efficacy and adverse effects in people with epilepsy treated with pregabalin (PGB) 300 mg per day (20 patients), alprazolam (ALP) 1,5 mg per day (20 patients) and P (18 patients). In this study several characteristics had been evaluated in each group: seizure frequency, severity of anxiety disorder and adverse effects of the drugs administrated. In 50-days therapy of epileptic patients PGB demonstrated high efficacy and safety in treatment pharmacoresistant epilepsy comorbid with mental disorders specifically in treatment epilepsy with generalized anxiety disorders. PGB proved to be safer compared with ALP since no habituation elaborated. In durable therapy of anxiety disorders in epilepsy PGB must be recommended. |
| format | Article |
| id | doaj-art-e58bf45c6b47434282347d7563a32eef |
| institution | Kabale University |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| publishDate | 2016-08-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj-art-e58bf45c6b47434282347d7563a32eef2025-08-20T03:57:32ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882016-08-01221724303PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSYM. Ya. Kissin0I. I. Bondarenko1I.P. Pavlov St. Petersburg State Medical UniversityI.P. Pavlov St. Petersburg State Medical UniversityHence anxiety disorders are frequently observed in the clinical picture of epilepsy these must be considered when choosing adequate therapy. Purpose of this study was evaluation therapeutic efficacy and adverse effects in people with epilepsy treated with pregabalin (PGB) 300 mg per day (20 patients), alprazolam (ALP) 1,5 mg per day (20 patients) and P (18 patients). In this study several characteristics had been evaluated in each group: seizure frequency, severity of anxiety disorder and adverse effects of the drugs administrated. In 50-days therapy of epileptic patients PGB demonstrated high efficacy and safety in treatment pharmacoresistant epilepsy comorbid with mental disorders specifically in treatment epilepsy with generalized anxiety disorders. PGB proved to be safer compared with ALP since no habituation elaborated. In durable therapy of anxiety disorders in epilepsy PGB must be recommended.https://www.epilepsia.su/jour/article/view/187epilepsygeneralized anxiety disorderantiepileptic drugsbenzodiazepinespregabalin |
| spellingShingle | M. Ya. Kissin I. I. Bondarenko PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY Эпилепсия и пароксизмальные состояния epilepsy generalized anxiety disorder antiepileptic drugs benzodiazepines pregabalin |
| title | PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY |
| title_full | PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY |
| title_fullStr | PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY |
| title_full_unstemmed | PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY |
| title_short | PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY |
| title_sort | pregabalin and alprazolam in treatment of generalized anxiety disorder in patients with partial epilepsy |
| topic | epilepsy generalized anxiety disorder antiepileptic drugs benzodiazepines pregabalin |
| url | https://www.epilepsia.su/jour/article/view/187 |
| work_keys_str_mv | AT myakissin pregabalinandalprazolamintreatmentofgeneralizedanxietydisorderinpatientswithpartialepilepsy AT iibondarenko pregabalinandalprazolamintreatmentofgeneralizedanxietydisorderinpatientswithpartialepilepsy |