Effect of thymol and Enterocin M administration on biochemical, antioxidant and immunological parameters, small intestinal morphology and microbiota in rabbits.
To find natural feed additives with a beneficial effect on rabbit health, thymol alone and in combination with Enterocin M were administered in drinking water for 42 days (35 -77 days of age). A total of 48 rabbits based on their weight were randomly divided into four experimental groups: C – contro...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Italian Journal of Animal Science |
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| Online Access: | http://dx.doi.org/10.1080/1828051X.2023.2257732 |
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| author | Kristina Bacova Karin Zitterl-Eglseer Andrea Laukova Lubica Chrastinova Sona Gancarcikova Rudolf Zitnan Margareta Takacsova Drahomira Sopkova Zuzana Andrejcakova Monika Pogany Simonova Radoslava Kristofova Zuzana Formelova Iveta Placha |
| author_facet | Kristina Bacova Karin Zitterl-Eglseer Andrea Laukova Lubica Chrastinova Sona Gancarcikova Rudolf Zitnan Margareta Takacsova Drahomira Sopkova Zuzana Andrejcakova Monika Pogany Simonova Radoslava Kristofova Zuzana Formelova Iveta Placha |
| author_sort | Kristina Bacova |
| collection | DOAJ |
| description | To find natural feed additives with a beneficial effect on rabbit health, thymol alone and in combination with Enterocin M were administered in drinking water for 42 days (35 -77 days of age). A total of 48 rabbits based on their weight were randomly divided into four experimental groups: C – control (basal diet), T – thymol (250 mg/L), E – Enterocin M (Ent M) (50 μL/animal/day), T + E (thymol with Ent M). Ent M (p < .05) and thymol (p < .01) separately decreased malondialdehyde in the liver. Thymol separately and in combination significantly increased phagocytic activity in the blood (p = .0051) and lactic acid in the caecum (p = .0142) and decreased coagulase-positive staphylococci in the caecum (p = .0329). Ent M separately and in combination increased immunoglobulin A content in the jejunal wall (p = .002) and decreased coliform bacteria in faeces (p = .0002). Thymol and Ent M application separately or in combination improved the antioxidant and immune response of rabbits and demonstrated an antibacterial effect. |
| format | Article |
| id | doaj-art-e58980d674194fa0a08bbb124532f5b9 |
| institution | Kabale University |
| issn | 1594-4077 1828-051X |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj-art-e58980d674194fa0a08bbb124532f5b92025-08-20T03:31:11ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2023-12-0122197298110.1080/1828051X.2023.22577322257732Effect of thymol and Enterocin M administration on biochemical, antioxidant and immunological parameters, small intestinal morphology and microbiota in rabbits.Kristina Bacova0Karin Zitterl-Eglseer1Andrea Laukova2Lubica Chrastinova3Sona Gancarcikova4Rudolf Zitnan5Margareta Takacsova6Drahomira Sopkova7Zuzana Andrejcakova8Monika Pogany Simonova9Radoslava Kristofova10Zuzana Formelova11Iveta Placha12Centre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Oddelenie fyziologie traviaceho traktuDepartment für Nutztiere und öffentliches Gesundheitswesen, Institute of Animal Nutrition and Functional Plant Compounds, University of Veterinary Medicine ViennaCentre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Oddelenie fyziologie traviaceho traktuNational Agricultural and Food CentreKatedra mikrobiologie a imunologie, University of Veterinary Medicine and PharmacyNational Agricultural and Food CentreCentre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Oddelenie fyziologie traviaceho traktuKatedra biologie a fyziologie, University of Veterinary Medicine and PharmacyKatedra biologie a fyziologie, University of Veterinary Medicine and PharmacyCentre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Oddelenie fyziologie traviaceho traktuCentre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Oddelenie fyziologie traviaceho traktuNational Agricultural and Food CentreCentre of Biosciences of the Slovak Academy of Sciences, Institute of Animal Physiology, Oddelenie fyziologie traviaceho traktuTo find natural feed additives with a beneficial effect on rabbit health, thymol alone and in combination with Enterocin M were administered in drinking water for 42 days (35 -77 days of age). A total of 48 rabbits based on their weight were randomly divided into four experimental groups: C – control (basal diet), T – thymol (250 mg/L), E – Enterocin M (Ent M) (50 μL/animal/day), T + E (thymol with Ent M). Ent M (p < .05) and thymol (p < .01) separately decreased malondialdehyde in the liver. Thymol separately and in combination significantly increased phagocytic activity in the blood (p = .0051) and lactic acid in the caecum (p = .0142) and decreased coagulase-positive staphylococci in the caecum (p = .0329). Ent M separately and in combination increased immunoglobulin A content in the jejunal wall (p = .002) and decreased coliform bacteria in faeces (p = .0002). Thymol and Ent M application separately or in combination improved the antioxidant and immune response of rabbits and demonstrated an antibacterial effect.http://dx.doi.org/10.1080/1828051X.2023.2257732natural additivesoxidative stressgut health |
| spellingShingle | Kristina Bacova Karin Zitterl-Eglseer Andrea Laukova Lubica Chrastinova Sona Gancarcikova Rudolf Zitnan Margareta Takacsova Drahomira Sopkova Zuzana Andrejcakova Monika Pogany Simonova Radoslava Kristofova Zuzana Formelova Iveta Placha Effect of thymol and Enterocin M administration on biochemical, antioxidant and immunological parameters, small intestinal morphology and microbiota in rabbits. Italian Journal of Animal Science natural additives oxidative stress gut health |
| title | Effect of thymol and Enterocin M administration on biochemical, antioxidant and immunological parameters, small intestinal morphology and microbiota in rabbits. |
| title_full | Effect of thymol and Enterocin M administration on biochemical, antioxidant and immunological parameters, small intestinal morphology and microbiota in rabbits. |
| title_fullStr | Effect of thymol and Enterocin M administration on biochemical, antioxidant and immunological parameters, small intestinal morphology and microbiota in rabbits. |
| title_full_unstemmed | Effect of thymol and Enterocin M administration on biochemical, antioxidant and immunological parameters, small intestinal morphology and microbiota in rabbits. |
| title_short | Effect of thymol and Enterocin M administration on biochemical, antioxidant and immunological parameters, small intestinal morphology and microbiota in rabbits. |
| title_sort | effect of thymol and enterocin m administration on biochemical antioxidant and immunological parameters small intestinal morphology and microbiota in rabbits |
| topic | natural additives oxidative stress gut health |
| url | http://dx.doi.org/10.1080/1828051X.2023.2257732 |
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