Progressive systemic inflammation precedes decompensation in compensated cirrhosis

Progressive systemic inflammation precedes decompensation in compensated cirrhosis

Background & Aims: Systemic inflammation is a driver of decompensation in cirrhosis with unclear relevance in the compensated stage. We evaluated inflammation and bacterial translocation markers in compensated cirrhosis and their dynamics in relation to the first decompensation. Methods: Thi...

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Main Authors: Rubén Sánchez-Aldehuelo, Càndid Villanueva, Joan Genescà, Juan Carlos García-Pagán, Elisa Castillo, José Luis Calleja, Carles Aracil, Rafael Bañares, Luis Téllez, Lorena Paule, Rosa María Morillas, María Poca, Beatriz Peñas, Salvador Augustin, Juan G. Abraldes, Edilmar Alvarado-Tapias, Jaume Bosch, Agustín Albillos
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:JHEP Reports
Subjects:
cytokine
bacterial translocation
portal hypertension
chronic advanced liver disease
immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555924002350
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