The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies
Abstract Morning awakening is part of everyday life. Surprisingly, information remains scarce on its underlying neurophysiological correlates. Here simultaneous polysomnography and stereo‐electroencephalography recordings from 18 patients are used to assess the spectral and connectivity content of t...
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| Format: | Article |
| Language: | English |
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Wiley
2025-05-01
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| Series: | Advanced Science |
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| Online Access: | https://doi.org/10.1002/advs.202409608 |
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| author | Tamir Avigdor Guoping Ren Chifaou Abdallah François Dubeau Christophe Grova Birgit Frauscher |
| author_facet | Tamir Avigdor Guoping Ren Chifaou Abdallah François Dubeau Christophe Grova Birgit Frauscher |
| author_sort | Tamir Avigdor |
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| description | Abstract Morning awakening is part of everyday life. Surprisingly, information remains scarce on its underlying neurophysiological correlates. Here simultaneous polysomnography and stereo‐electroencephalography recordings from 18 patients are used to assess the spectral and connectivity content of the process of awakening at a local level 15 min before and after the awakening. Awakenings from non‐rapid eye movement sleep are accompanied by a widespread increase in ripple (>80 Hz) power in the fronto‐temporal and parieto‐insular regions, with connectivity showing an almost exclusive increase in the ripple band in the somatomotor, default, dorsal attention, and frontoparietal networks. Awakenings from rapid eye movement sleep are characterized by a widespread and almost exclusive increase in the ripple band in all available brain lobes, and connectivity increases mainly in the low ripple band in the limbic system as well as the default, dorsal attention, somatomotor, and frontoparietal networks. |
| format | Article |
| id | doaj-art-e582da8e8c2f454b91f37895a05841b5 |
| institution | Kabale University |
| issn | 2198-3844 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj-art-e582da8e8c2f454b91f37895a05841b52025-08-20T03:47:33ZengWileyAdvanced Science2198-38442025-05-011219n/an/a10.1002/advs.202409608The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High FrequenciesTamir Avigdor0Guoping Ren1Chifaou Abdallah2François Dubeau3Christophe Grova4Birgit Frauscher5Analytical Neurophysiology Lab McGill University Montreal QC H3A 2B4 CanadaDepartment of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100070 ChinaAnalytical Neurophysiology Lab McGill University Montreal QC H3A 2B4 CanadaMontreal Neurological Institute and Hospital McGill University Montreal QC H3A 2B4 CanadaMultimodal Functional Imaging Lab Biomedical Engineering Department McGill University Montreal QC H3A 2B4 CanadaAnalytical Neurophysiology Lab McGill University Montreal QC H3A 2B4 CanadaAbstract Morning awakening is part of everyday life. Surprisingly, information remains scarce on its underlying neurophysiological correlates. Here simultaneous polysomnography and stereo‐electroencephalography recordings from 18 patients are used to assess the spectral and connectivity content of the process of awakening at a local level 15 min before and after the awakening. Awakenings from non‐rapid eye movement sleep are accompanied by a widespread increase in ripple (>80 Hz) power in the fronto‐temporal and parieto‐insular regions, with connectivity showing an almost exclusive increase in the ripple band in the somatomotor, default, dorsal attention, and frontoparietal networks. Awakenings from rapid eye movement sleep are characterized by a widespread and almost exclusive increase in the ripple band in all available brain lobes, and connectivity increases mainly in the low ripple band in the limbic system as well as the default, dorsal attention, somatomotor, and frontoparietal networks.https://doi.org/10.1002/advs.202409608awakeningconnectivityintracranial EEGsleepspectral analysis |
| spellingShingle | Tamir Avigdor Guoping Ren Chifaou Abdallah François Dubeau Christophe Grova Birgit Frauscher The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies Advanced Science awakening connectivity intracranial EEG sleep spectral analysis |
| title | The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies |
| title_full | The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies |
| title_fullStr | The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies |
| title_full_unstemmed | The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies |
| title_short | The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies |
| title_sort | awakening brain is characterized by a widespread and spatiotemporally heterogeneous increase in high frequencies |
| topic | awakening connectivity intracranial EEG sleep spectral analysis |
| url | https://doi.org/10.1002/advs.202409608 |
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