Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery

Background/aims To examine demographic and clinical factors associated with ocular pain 1 day after refractive surgery.Methods Prospective study of individuals undergoing refractive surgery. Participants rated their ocular pain on a 0–10 numerical rating scale (NRS) presurgery and 1 day after surger...

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Main Authors: Anat Galor, Jodi Lapidus, Winston Chamberlain, Elyana Vittoria Tessa Locatelli, Jason Betz, Brooke M Harkness, Maricarmen Perez-Blanco, Steven J Everist, Siting Chen, Richard Stutzman, Afshan Nanji, Sue A Aicher
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:BMJ Open Ophthalmology
Online Access:https://bmjophth.bmj.com/content/9/1/e001624.full
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author Anat Galor
Jodi Lapidus
Winston Chamberlain
Elyana Vittoria Tessa Locatelli
Jason Betz
Brooke M Harkness
Maricarmen Perez-Blanco
Steven J Everist
Siting Chen
Richard Stutzman
Afshan Nanji
Sue A Aicher
author_facet Anat Galor
Jodi Lapidus
Winston Chamberlain
Elyana Vittoria Tessa Locatelli
Jason Betz
Brooke M Harkness
Maricarmen Perez-Blanco
Steven J Everist
Siting Chen
Richard Stutzman
Afshan Nanji
Sue A Aicher
author_sort Anat Galor
collection DOAJ
description Background/aims To examine demographic and clinical factors associated with ocular pain 1 day after refractive surgery.Methods Prospective study of individuals undergoing refractive surgery. Participants rated their ocular pain on a 0–10 numerical rating scale (NRS) presurgery and 1 day after surgery. Presurgery, participants completed questionnaires on demographics, comorbidities, medications and dry eye and ocular pain symptoms; and an anaesthetised Schirmer test was performed. Acute ocular pain 1 day after surgery was defined as an NRS score of worst pain since surgery ≥3 and this group was compared with individuals with NRS scores<3.Results 251 individuals underwent refractive surgery (89% laser-assisted in situ keratomileusis, n=222; 11% PRK, n=29). Mean age was 35±8 years (range 19 to 60); 60% (n=150) self-identified as female, 80% (n=203) as White, and 36% (n=89) as Hispanic. Thirteen (5%) individuals reported ocular pain (NRS ≥3) prior to surgery and 67% (n=168) reported ocular pain 1 day after surgery (nine individuals had pain at both time points). Factors that were associated with pain 1 day after surgery included Hispanic ethnicity (adjusted relative risk (aRR) 1.42, 95% CI 1.21 to 1.68, p<0.001) and the presence of eye pain presurgery (aRR 1.10, 95% CI 1.02 to 1.18, p=0.02).Conclusion A majority of individuals report moderate or greater pain within 24 hours of refractive surgery. Hispanic ethnicity and eye pain prior to surgery were associated with self-reported acute postsurgical pain.
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spelling doaj-art-e582073f70b24b3590ddde71891126d02025-02-06T10:15:11ZengBMJ Publishing GroupBMJ Open Ophthalmology2397-32692024-03-019110.1136/bmjophth-2023-001624Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgeryAnat Galor0Jodi Lapidus1Winston Chamberlain2Elyana Vittoria Tessa Locatelli3Jason Betz4Brooke M Harkness5Maricarmen Perez-Blanco6Steven J Everist7Siting Chen8Richard Stutzman9Afshan Nanji10Sue A Aicher11Ophthalmology, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, USASchool of Public Health, Oregon Health & Science University, Portland, Oregon, USAOphthalmology, Oregon Health & Science University Casey Eye Institute, Portland, Oregon, USAOphthalmology, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, USAOphthalmology, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, USACasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USAOphthalmology, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, USADepartment of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, Oregon, USASchool of Public Health, Oregon Health & Science University, Portland, Oregon, USACasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USACasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USADepartment of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, Oregon, USABackground/aims To examine demographic and clinical factors associated with ocular pain 1 day after refractive surgery.Methods Prospective study of individuals undergoing refractive surgery. Participants rated their ocular pain on a 0–10 numerical rating scale (NRS) presurgery and 1 day after surgery. Presurgery, participants completed questionnaires on demographics, comorbidities, medications and dry eye and ocular pain symptoms; and an anaesthetised Schirmer test was performed. Acute ocular pain 1 day after surgery was defined as an NRS score of worst pain since surgery ≥3 and this group was compared with individuals with NRS scores<3.Results 251 individuals underwent refractive surgery (89% laser-assisted in situ keratomileusis, n=222; 11% PRK, n=29). Mean age was 35±8 years (range 19 to 60); 60% (n=150) self-identified as female, 80% (n=203) as White, and 36% (n=89) as Hispanic. Thirteen (5%) individuals reported ocular pain (NRS ≥3) prior to surgery and 67% (n=168) reported ocular pain 1 day after surgery (nine individuals had pain at both time points). Factors that were associated with pain 1 day after surgery included Hispanic ethnicity (adjusted relative risk (aRR) 1.42, 95% CI 1.21 to 1.68, p<0.001) and the presence of eye pain presurgery (aRR 1.10, 95% CI 1.02 to 1.18, p=0.02).Conclusion A majority of individuals report moderate or greater pain within 24 hours of refractive surgery. Hispanic ethnicity and eye pain prior to surgery were associated with self-reported acute postsurgical pain.https://bmjophth.bmj.com/content/9/1/e001624.full
spellingShingle Anat Galor
Jodi Lapidus
Winston Chamberlain
Elyana Vittoria Tessa Locatelli
Jason Betz
Brooke M Harkness
Maricarmen Perez-Blanco
Steven J Everist
Siting Chen
Richard Stutzman
Afshan Nanji
Sue A Aicher
Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery
BMJ Open Ophthalmology
title Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery
title_full Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery
title_fullStr Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery
title_full_unstemmed Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery
title_short Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery
title_sort prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery
url https://bmjophth.bmj.com/content/9/1/e001624.full
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