Role and prognostic value of growth differentiation factor 15 in patient of heart failure with preserved ejection fraction: insights from the PURSUIT-HFpEF registry

Role and prognostic value of growth differentiation factor 15 in patient of heart failure with preserved ejection fraction: insights from the PURSUIT-HFpEF registry

Background Growth differentiation factor 15 (GDF15) is a cytokine responding to oxidative stress and inflammation, and it regulates appetite and energy balance. The association between GDF15 and clinical factors and its prognostic value in elderly multimorbid patients with heart failure with preserv...

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Main Authors: Tetsuhisa Kitamura, Shungo Hikoso, Takahisa Yamada, Yoshio Yasumura, Akito Nakagawa, Toshihiro Takeda, Hirota Kida, Akihiro Sunaga, Tomoharu Dohi, Katsuki Okada, Daisaku Nakatani, Yasushi Matsumura, Yasushi Sakata, Shunsuke Tamaki, Takaharu Hayashi, Yoshiharu Higuchi, Masaharu Masuda, Mitsutoshi Asai, Toshiaki Mano, Hisakazu Fuji, Daisaku Masuda, Shizuya Yamashita, Masami Sairyo, Yusuke Nakagawa, Haruhiko Abe, Yasunori Ueda, Kunihiko Nagai, Masamichi Yano, Masami Nishino, Jun Tanouchi, Yoh Arita, Shinji Hasegawa, Takamaru Ishizu, Minoru Ichikawa, Yuzuru Takano, Eisai Rin, Tetsuya Watanabe, Shiro Hoshida, Masahiro Izumi, Hiroyoshi Yamamoto, Hiroyasu Kato, Kazuhiro Nakatani, Mayu Nishio, Keiji Hirooka, Takahiro Yoshimura, Akihiro Tani, Yasushi Okumoto, Yasunaka Makino, Katsuomi Iwakura, Yoshiyuki Kijima, Takashi Kitao, Masashi Fujita, Koichiro Harada, Masahiro Kumada, Osamu Nakagawa, Ryo Araki, Takayuki Yamada, Fusako Sera, Kei Nakamoto, Hidetaka Kioka, Tomohito Ohtani, Nobuyuki Ogasawara, Yukinori Shinoda, Koichi Tachibana, Yohei Sotomi, Taiki Sato, Yuji Yasuga, Toshinari Onishi, Kazunori Kashiwase, Ryu Shutta, Masahiro Seo, Yuki Matsuoka, Yasuhiro Akazawa, Daisuke Sakamoto
Format: Article
Language:English
Published: BMJ Publishing Group 2025-01-01
Series:Open Heart
Online Access:https://openheart.bmj.com/content/12/1/e003008.full
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