Association between physical activity level and cardiovascular disease: An empirical analysis based on CHARLS data in 2018.

<h4>Objective</h4>Cardiovascular disease (CVD) was a global public health challenge. This study aimed to investigate the association between physical activity level (PAL) and CVD among middle-aged and older adults in China, to provide evidence to inform strategies for CVD prevention and...

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Main Authors: Haiwei Li, Liang Luo, Jing Zhang, Yanhao Zhao, Peipei Cheng, Dan Liu, Liwei Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329232
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Summary:<h4>Objective</h4>Cardiovascular disease (CVD) was a global public health challenge. This study aimed to investigate the association between physical activity level (PAL) and CVD among middle-aged and older adults in China, to provide evidence to inform strategies for CVD prevention and management.<h4>Methods</h4>The diagnosis of CVD was based on self-reported physician-diagnosed heart disease or stroke, while PAL were classified using calculations derived from a structured questionnaire. Both datasets were obtained from the 2018 China Health and Retirement Longitudinal Study (CHARLS) survey. A multivariate logistic regression model was used for the primary correlation analysis. Additionally, restricted cubic spline (RCS) regression was employed to examine the potential nonlinear association between PAL and CVD.<h4>Results</h4>The final analysis included 9,015 participants, 1,069 of whom were diagnosed with CVD, yielding a prevalence of 11.86%. After adjusting for all covariates, the multivariate-adjusted odds ratios (ORs) for the moderate PAL group (600-3000 MET-minutes/week) and the high PAL group (>3000 MET-minutes/week) were 0.79 (95% CI: 0.64-0.97) and 0.72 (95% CI: 0.60-0.87), respectively, compared to the low PAL group (<600 MET-minutes/week). Furthermore, restricted cubic spline analysis revealed a significant linear relationship between PAL and CVD (nonlinear P > 0.05), indicating that the OR for CVD decreased with higher levels of PAL.<h4>Conclusions</h4>This study revealed a negative correlation between PAL and the prevalence of CVD. Furthermore, our findings suggested that middle-aged and older adults should maintain moderate to high levels of physical activity, as this was associated with a lower risk of CVD.
ISSN:1932-6203