Modeling the Human Kinetic Adjustment Factor for Inhaled Volatile Organic Chemicals: Whole Population Approach versus Distinct Subpopulation Approach

The objective of this study was to evaluate the impact of whole- and sub-population-related variabilities on the determination of the human kinetic adjustment factor (HKAF) used in risk assessment of inhaled volatile organic chemicals (VOCs). Monte Carlo simulations were applied to a steady-state al...

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Bibliographic Details
Main Authors: M. Valcke, A. Nong, K. Krishnan
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2012/404329
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