Microplastics to Metabolomics: Understanding the environmental and health implications of plastic pollution
Microplastics (MPs) are composed of solid plastic fragments that are smaller than 5 mm and are insoluble in water. MPs have acquired more attention in recent years, due to their pervasiveness in the environment. There are worries regarding the potential health effects of these particles on humans be...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Polymer Testing |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0142941825002326 |
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| author | Ashish Gaur Nishant Singhal Rajat Singh Rajul Jain Narpinder Singh Gaurav Pant Arun Karnwal Tabarak Malik |
| author_facet | Ashish Gaur Nishant Singhal Rajat Singh Rajul Jain Narpinder Singh Gaurav Pant Arun Karnwal Tabarak Malik |
| author_sort | Ashish Gaur |
| collection | DOAJ |
| description | Microplastics (MPs) are composed of solid plastic fragments that are smaller than 5 mm and are insoluble in water. MPs have acquired more attention in recent years, due to their pervasiveness in the environment. There are worries regarding the potential health effects of these particles on humans because they have been discovered in various food products and water sources. So, a comprehensive method for researching the biochemical effects of MP exposure is provided by metabolomics, an analytical technique that is useful for analyzing metabolites within biological systems. This review explores the application of metabolomics to the investigation of the biological consequences of Microplastic (MP) pollution. It looks at metabolomics methods, both targeted and untargeted, that offer a thorough examination of the metabolites impacted by MP exposure. The review also examines the potential health risks—such as oxidative stress, immune system disruption, and metabolic problems—associated with MP exposure. It highlights the need for additional study to elucidate the long-term health consequences of MP exposure. This review provides a comprehensive understanding of the biological effects of MP contamination and its wider ecological and health implications by combining metabolomics with environmental research. |
| format | Article |
| id | doaj-art-e5676377fb2c4675935177614aa2c036 |
| institution | Kabale University |
| issn | 1873-2348 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Polymer Testing |
| spelling | doaj-art-e5676377fb2c4675935177614aa2c0362025-08-20T03:36:26ZengElsevierPolymer Testing1873-23482025-09-0115010891810.1016/j.polymertesting.2025.108918Microplastics to Metabolomics: Understanding the environmental and health implications of plastic pollutionAshish Gaur0Nishant Singhal1Rajat Singh2Rajul Jain3Narpinder Singh4Gaurav Pant5Arun Karnwal6Tabarak Malik7Department of Biotechnology, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, IndiaDepartment of Biochemistry, Banaras Hindu University, Varanasi, 221005, IndiaGurukula Kangri (Deemed to be University), Haridwar, IndiaDept. of Zoology, Dayalbagh Educational Institute, Agra, Uttar Pradesh, IndiaDepartment of Food Science and Technology, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, IndiaDepartment of Microbiology, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, India; Corresponding author.Department of Microbiology, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, India; Corresponding authors.Department of Biomedical Sciences, Institute of Health, Jimma University, Ethiopia; Division of Research and Development, Lovely Professional University,Phagwara, Punjab-144401 India; Corresponding author.Microplastics (MPs) are composed of solid plastic fragments that are smaller than 5 mm and are insoluble in water. MPs have acquired more attention in recent years, due to their pervasiveness in the environment. There are worries regarding the potential health effects of these particles on humans because they have been discovered in various food products and water sources. So, a comprehensive method for researching the biochemical effects of MP exposure is provided by metabolomics, an analytical technique that is useful for analyzing metabolites within biological systems. This review explores the application of metabolomics to the investigation of the biological consequences of Microplastic (MP) pollution. It looks at metabolomics methods, both targeted and untargeted, that offer a thorough examination of the metabolites impacted by MP exposure. The review also examines the potential health risks—such as oxidative stress, immune system disruption, and metabolic problems—associated with MP exposure. It highlights the need for additional study to elucidate the long-term health consequences of MP exposure. This review provides a comprehensive understanding of the biological effects of MP contamination and its wider ecological and health implications by combining metabolomics with environmental research.http://www.sciencedirect.com/science/article/pii/S0142941825002326MicroplasticsMetabolomicsFood contaminationDietary exposureBioaccumulation |
| spellingShingle | Ashish Gaur Nishant Singhal Rajat Singh Rajul Jain Narpinder Singh Gaurav Pant Arun Karnwal Tabarak Malik Microplastics to Metabolomics: Understanding the environmental and health implications of plastic pollution Polymer Testing Microplastics Metabolomics Food contamination Dietary exposure Bioaccumulation |
| title | Microplastics to Metabolomics: Understanding the environmental and health implications of plastic pollution |
| title_full | Microplastics to Metabolomics: Understanding the environmental and health implications of plastic pollution |
| title_fullStr | Microplastics to Metabolomics: Understanding the environmental and health implications of plastic pollution |
| title_full_unstemmed | Microplastics to Metabolomics: Understanding the environmental and health implications of plastic pollution |
| title_short | Microplastics to Metabolomics: Understanding the environmental and health implications of plastic pollution |
| title_sort | microplastics to metabolomics understanding the environmental and health implications of plastic pollution |
| topic | Microplastics Metabolomics Food contamination Dietary exposure Bioaccumulation |
| url | http://www.sciencedirect.com/science/article/pii/S0142941825002326 |
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