Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese
ABSTRACT Background: The treatment of Parkinson disease with dopaminergic therapy improves functionality and quality of life. However, as the disease progresses, the wearing-off phenomenon develops. To improve the recognition of this phenomenon, the 19-item wearing-off questionnaire (WOQ-19) was d...
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| Language: | English |
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Thieme Revinter Publicações
2020-09-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020001000624&tlng=en |
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| author | Carlos Eduardo MANTESE Marcio MEDEIROS Artur SCHUMACHER-SCHUH Carlos Roberto de Melo RIEDER |
| author_facet | Carlos Eduardo MANTESE Marcio MEDEIROS Artur SCHUMACHER-SCHUH Carlos Roberto de Melo RIEDER |
| author_sort | Carlos Eduardo MANTESE |
| collection | DOAJ |
| description | ABSTRACT Background: The treatment of Parkinson disease with dopaminergic therapy improves functionality and quality of life. However, as the disease progresses, the wearing-off phenomenon develops. To improve the recognition of this phenomenon, the 19-item wearing-off questionnaire (WOQ-19) was developed. Objective: To translate and validate the WOQ-19 into Portuguese. Methods: The questionnaire was translated into Portuguese and, subsequently, back-translated into English and analyzed. The final version was tested in Parkinson disease patients for reliability through the test-retest paradigm and internal consistency. Also, sensitivity and specificity were obtained in different cut-off positive items. Results: The WOQ-19 showed good test stability, with an intraclass correlation coefficient of 0.877 (95%CI 0.690-0.951; p<0.001), and good internal consistency, with Cronbach alpha of 0.815. Two items of positive cut-off showed the best accuracy: 0.873 (95%CI 0.791-0.954). Sensitivity was 0.975 (95%CI 0.892-1) and specificity was 0.714 (95%CI 0.565-0.863). Conclusion: The Portuguese version of the WOQ-19 showed excellent diagnostic properties and can be used to diagnose wearing-off phenomena. |
| format | Article |
| id | doaj-art-e5671d50f3b34656a96935ddc3622dde |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-e5671d50f3b34656a96935ddc3622dde2025-08-20T03:25:02ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272020-09-01781062462810.1590/0004-282x20200045Validation of 19-items wearing-off (WOQ-19) questionnaire to PortugueseCarlos Eduardo MANTESEhttps://orcid.org/0000-0002-8306-803XMarcio MEDEIROShttps://orcid.org/0000-0001-5733-9468Artur SCHUMACHER-SCHUHhttps://orcid.org/0000-0002-8722-0908Carlos Roberto de Melo RIEDERhttps://orcid.org/0000-0003-2950-7211ABSTRACT Background: The treatment of Parkinson disease with dopaminergic therapy improves functionality and quality of life. However, as the disease progresses, the wearing-off phenomenon develops. To improve the recognition of this phenomenon, the 19-item wearing-off questionnaire (WOQ-19) was developed. Objective: To translate and validate the WOQ-19 into Portuguese. Methods: The questionnaire was translated into Portuguese and, subsequently, back-translated into English and analyzed. The final version was tested in Parkinson disease patients for reliability through the test-retest paradigm and internal consistency. Also, sensitivity and specificity were obtained in different cut-off positive items. Results: The WOQ-19 showed good test stability, with an intraclass correlation coefficient of 0.877 (95%CI 0.690-0.951; p<0.001), and good internal consistency, with Cronbach alpha of 0.815. Two items of positive cut-off showed the best accuracy: 0.873 (95%CI 0.791-0.954). Sensitivity was 0.975 (95%CI 0.892-1) and specificity was 0.714 (95%CI 0.565-0.863). Conclusion: The Portuguese version of the WOQ-19 showed excellent diagnostic properties and can be used to diagnose wearing-off phenomena.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020001000624&tlng=enParkinson DiseaseAntiparkinson Agents |
| spellingShingle | Carlos Eduardo MANTESE Marcio MEDEIROS Artur SCHUMACHER-SCHUH Carlos Roberto de Melo RIEDER Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese Arquivos de Neuro-Psiquiatria Parkinson Disease Antiparkinson Agents |
| title | Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese |
| title_full | Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese |
| title_fullStr | Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese |
| title_full_unstemmed | Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese |
| title_short | Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese |
| title_sort | validation of 19 items wearing off woq 19 questionnaire to portuguese |
| topic | Parkinson Disease Antiparkinson Agents |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020001000624&tlng=en |
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