Effect of the long-term storage methods on the stability of cartilage biomechanical parameters

Long-term stability of the tissue product in terms of mechanical parameters is a key factor for its expiration date. For the investigation of storage effects on the cartilage tissues the experimental mechanical loading test combined with XCT scanning for the irregular shape inspection was performed...

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Main Authors: Blanka Žaloudková, Šárka Sekorová, Barbora Kopecká, Daniel Kytýř
Format: Article
Language:English
Published: Czech Technical University in Prague 2023-10-01
Series:Acta Polytechnica CTU Proceedings
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Online Access:https://ojs.cvut.cz/ojs/index.php/APP/article/view/9408
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author Blanka Žaloudková
Šárka Sekorová
Barbora Kopecká
Daniel Kytýř
author_facet Blanka Žaloudková
Šárka Sekorová
Barbora Kopecká
Daniel Kytýř
author_sort Blanka Žaloudková
collection DOAJ
description Long-term stability of the tissue product in terms of mechanical parameters is a key factor for its expiration date. For the investigation of storage effects on the cartilage tissues the experimental mechanical loading test combined with XCT scanning for the irregular shape inspection was performed. The samples were preserved according to three different protocols using the deep-freezing and two types of saline solution preservation. The stability of the biomechanical parameters was tested within annual intervals. All samples were subjected to uni-axial compression loading using the in-house developed compact table top loading device in displacement-driven mode. Based on the measurements, the results are represented in the form of stress-strain curves and quantified as elastic modulus and ultimate compression stress. It can be concluded that no significant difference was found in neither the mechanical properties of the samples nor in the effects of each preservational method.
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institution Kabale University
issn 2336-5382
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publishDate 2023-10-01
publisher Czech Technical University in Prague
record_format Article
series Acta Polytechnica CTU Proceedings
spelling doaj-art-e5584fd2501f4509bac7b8f12f4dd97a2025-08-20T03:57:59ZengCzech Technical University in PragueActa Polytechnica CTU Proceedings2336-53822023-10-014210.14311/APP.2023.42.0094Effect of the long-term storage methods on the stability of cartilage biomechanical parametersBlanka Žaloudková0Šárka Sekorová1Barbora Kopecká2Daniel Kytýř3Czech Academy of Sciences, Institute of Theoretical and Applied Mechanics, Prosecká 76, 190 00 Prague, Czech Republic; Czech Technical University in Prague, Faculty of Transportation Sciences, Mobile Laboratory for Transport Analysis, Konviktská 20, 110 00 Prague, Czech RepublicNational Cell and Tissue Centre, Dr. Slabihoudka 6232/11, 708 00 Ostrava, Czech RepublicNational Cell and Tissue Centre, Dr. Slabihoudka 6232/11, 708 00 Ostrava, Czech RepublicCzech Academy of Sciences, Institute of Theoretical and Applied Mechanics, Prosecká 76, 190 00 Prague, Czech Republic Long-term stability of the tissue product in terms of mechanical parameters is a key factor for its expiration date. For the investigation of storage effects on the cartilage tissues the experimental mechanical loading test combined with XCT scanning for the irregular shape inspection was performed. The samples were preserved according to three different protocols using the deep-freezing and two types of saline solution preservation. The stability of the biomechanical parameters was tested within annual intervals. All samples were subjected to uni-axial compression loading using the in-house developed compact table top loading device in displacement-driven mode. Based on the measurements, the results are represented in the form of stress-strain curves and quantified as elastic modulus and ultimate compression stress. It can be concluded that no significant difference was found in neither the mechanical properties of the samples nor in the effects of each preservational method. https://ojs.cvut.cz/ojs/index.php/APP/article/view/9408stability studycartilagebiomechanical characterisationcompression loadingXCT imaging
spellingShingle Blanka Žaloudková
Šárka Sekorová
Barbora Kopecká
Daniel Kytýř
Effect of the long-term storage methods on the stability of cartilage biomechanical parameters
Acta Polytechnica CTU Proceedings
stability study
cartilage
biomechanical characterisation
compression loading
XCT imaging
title Effect of the long-term storage methods on the stability of cartilage biomechanical parameters
title_full Effect of the long-term storage methods on the stability of cartilage biomechanical parameters
title_fullStr Effect of the long-term storage methods on the stability of cartilage biomechanical parameters
title_full_unstemmed Effect of the long-term storage methods on the stability of cartilage biomechanical parameters
title_short Effect of the long-term storage methods on the stability of cartilage biomechanical parameters
title_sort effect of the long term storage methods on the stability of cartilage biomechanical parameters
topic stability study
cartilage
biomechanical characterisation
compression loading
XCT imaging
url https://ojs.cvut.cz/ojs/index.php/APP/article/view/9408
work_keys_str_mv AT blankazaloudkova effectofthelongtermstoragemethodsonthestabilityofcartilagebiomechanicalparameters
AT sarkasekorova effectofthelongtermstoragemethodsonthestabilityofcartilagebiomechanicalparameters
AT barborakopecka effectofthelongtermstoragemethodsonthestabilityofcartilagebiomechanicalparameters
AT danielkytyr effectofthelongtermstoragemethodsonthestabilityofcartilagebiomechanicalparameters