Effect of atmospheric particulate matter on the functional state of mitochondria

The health risks associated with outdoor air pollution are of global concern. Atmospheric air pollution negatively affects a number of key aspects of human health, including the functioning of the respiratory, cardiovascular and central nervous systems, but many issues remain unresolved about the re...

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Main Authors: Elena V. Kondratyeva, Tatyana I. Vitkina
Format: Article
Language:English
Published: Limited liability company «Science and Innovations» (Saratov) 2023-03-01
Series:Russian Open Medical Journal
Subjects:
Online Access:https://romj.org/node/518
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author Elena V. Kondratyeva
Tatyana I. Vitkina
author_facet Elena V. Kondratyeva
Tatyana I. Vitkina
author_sort Elena V. Kondratyeva
collection DOAJ
description The health risks associated with outdoor air pollution are of global concern. Atmospheric air pollution negatively affects a number of key aspects of human health, including the functioning of the respiratory, cardiovascular and central nervous systems, but many issues remain unresolved about the relationship between atmospheric air pollution and the development and course of pathologies. The review analyzes data from Russian and foreign sources on the effect of atmospheric particulate matter on the functional state of mitochondria. The effect of air pollution on structural changes in mitochondria, ATP synthesis, production of reactive oxygen species, damage to mitochondrial DNA, and mitochondrial membrane potential has been shown. The data presented in the review indicate the need for further studies of the functional state of mitochondria under the impact of solid particles in atmospheric air.
format Article
id doaj-art-e54e83b643d747e49e3209252368cfad
institution DOAJ
issn 2304-3415
language English
publishDate 2023-03-01
publisher Limited liability company «Science and Innovations» (Saratov)
record_format Article
series Russian Open Medical Journal
spelling doaj-art-e54e83b643d747e49e3209252368cfad2025-08-20T03:19:17ZengLimited liability company «Science and Innovations» (Saratov)Russian Open Medical Journal2304-34152023-03-01121e010610.15275/rusomj.2023.0106Effect of atmospheric particulate matter on the functional state of mitochondriaElena V. KondratyevaTatyana I. VitkinaThe health risks associated with outdoor air pollution are of global concern. Atmospheric air pollution negatively affects a number of key aspects of human health, including the functioning of the respiratory, cardiovascular and central nervous systems, but many issues remain unresolved about the relationship between atmospheric air pollution and the development and course of pathologies. The review analyzes data from Russian and foreign sources on the effect of atmospheric particulate matter on the functional state of mitochondria. The effect of air pollution on structural changes in mitochondria, ATP synthesis, production of reactive oxygen species, damage to mitochondrial DNA, and mitochondrial membrane potential has been shown. The data presented in the review indicate the need for further studies of the functional state of mitochondria under the impact of solid particles in atmospheric air.https://romj.org/node/518mitochondriafatty acidsmitochondrial dysfunctionmitochondrial membrane potentialmitochondrial dna damageatmospheric particulate matter
spellingShingle Elena V. Kondratyeva
Tatyana I. Vitkina
Effect of atmospheric particulate matter on the functional state of mitochondria
Russian Open Medical Journal
mitochondria
fatty acids
mitochondrial dysfunction
mitochondrial membrane potential
mitochondrial dna damage
atmospheric particulate matter
title Effect of atmospheric particulate matter on the functional state of mitochondria
title_full Effect of atmospheric particulate matter on the functional state of mitochondria
title_fullStr Effect of atmospheric particulate matter on the functional state of mitochondria
title_full_unstemmed Effect of atmospheric particulate matter on the functional state of mitochondria
title_short Effect of atmospheric particulate matter on the functional state of mitochondria
title_sort effect of atmospheric particulate matter on the functional state of mitochondria
topic mitochondria
fatty acids
mitochondrial dysfunction
mitochondrial membrane potential
mitochondrial dna damage
atmospheric particulate matter
url https://romj.org/node/518
work_keys_str_mv AT elenavkondratyeva effectofatmosphericparticulatematteronthefunctionalstateofmitochondria
AT tatyanaivitkina effectofatmosphericparticulatematteronthefunctionalstateofmitochondria