Osteoarticular involvement of brucellosis in pediatric patients: clinical and laboratory characteristics
Background and Objectives. The aim of this study was to evaluate the clinical and laboratory characteristics of osteoarticular involvement in children with brucellosis. Methods. A total of 202 pediatric brucellosis patients were evaluated from April 2012 to August 2013. Results....
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Hacettepe University Institute of Child Health
2020-04-01
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| Series: | The Turkish Journal of Pediatrics |
| Subjects: | |
| Online Access: | https://turkjpediatr.org/article/view/433 |
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| Summary: | Background and Objectives. The aim of this study was to evaluate the clinical and laboratory characteristics of osteoarticular involvement in children with brucellosis.
Methods. A total of 202 pediatric brucellosis patients were evaluated from April 2012 to August 2013.
Results. Among the 202 patients, 53 (26.2%) had osteoarticular involvement. In patients with osteoarticular involvement, the mean values of estimated sedimentation rate (ESR) and C-reactive protein (C-RP) were significantly higher than in patients without osteoarticular involvement (p = 0.001, p = 0.01, respectively). The majority of patients with osteoarticular involvement (n = 48, 90.6%) had a higher standard tube agglutination (STA) test titer (≥ 1/640) than patients without osteoarticular involvement (n = 69, 46.3%) (p = 0.001). The most commonly found osteoarticular involvement was peripheral arthritis. The second most commonly found osteoarticular involvement was sacroiliitis (n = 5, 9.4%). Three patients (5.7%) had spondylitis. Only one patient (1.9%) had osteomyelitis.
Conclusions. Osteoarticular involvement was detected in nearly one of every four childhood brucellosis patients in our study. Brucellosis should be considered as a pre-diagnosis in children with osteoarticular complaints, especially in regions where the disease is endemic.
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| ISSN: | 0041-4301 2791-6421 |