Time Course of Plasma Proteomic and Oxylipin Changes Induced by LPS Challenge and Modulated by Antioxidant Supplementation in a Randomized Controlled Trial

Time Course of Plasma Proteomic and Oxylipin Changes Induced by LPS Challenge and Modulated by Antioxidant Supplementation in a Randomized Controlled Trial

Systemic molecular responses to pathogen-associated molecular patterns and their modulation by antioxidants are poorly understood in humans. Here, we present a two-stage clinical interventional study in healthy humans challenged with lipopolysaccharide. In the first step, the kinetics of inflammator...

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Bibliographic Details
Main Authors: Gerhard Hagn, Andrea Bileck, Thomas Mohr, Doreen Schmidl, David M. Baron, Bernd Jilma, Leopold Schmetterer, Gerhard Garhöfer, Christopher Gerner
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Antioxidants
Subjects:
antioxidant supplementation
inflammation
Lands cycle
lipids
lipopolysaccharide
oxylipins
Online Access:https://www.mdpi.com/2076-3921/14/5/536
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