BPA and low-Se exacerbate apoptosis and mitophagy in chicken pancreatic cells by regulating the PTEN/PI3K/AKT/mTOR pathway

BPA and low-Se exacerbate apoptosis and mitophagy in chicken pancreatic cells by regulating the PTEN/PI3K/AKT/mTOR pathway

Introduction: Bisphenol A (BPA) is a widespread environmental pollutant which has serious toxic effects on organisms. One of the crucial trace elements is selenium (Se), whose shortage can harm biological tissues and enhance the toxicity of contaminants, in which apoptosis and autophagy are core eve...

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Bibliographic Details
Main Authors: Wenying Sun, Yutian Lei, Zhihui Jiang, Kun Wang, Huanyi Liu, Tong Xu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Advanced Research
Subjects:
Apoptosis
Bisphenol A
Low-Se
Mitophagy
PTEN/PI3K/AKT/mTOR
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224000420
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